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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Background: Monte Carlo (MC) simulation is the most accurate for calculating radiation dose distribution and determining patient dose. In MC simulations of the therapeutic accelerator, the characteristics of the initial electron must be precisely determined in order to achieve accurate simulations. However, It has been computation-, labor-, and time-intensive to predict the beam characteristics through predominantly empirical approach. The aim of this study was to analyze the relationships between electron beam parameters and dose distribution, with the goal of simplifying the MC commissioning process. Materials and Methods: The Varian Clinac 2300 IX machine was modeled with the Geant4 MC-toolkit. The percent depth dose (PDD) and lateral beam profiles were assessed according to initial electron beam parameters of mean energy, radial intensity distribution, and energy distribution. Results and Discussion: The PDD values increased on average by 4.36% when the mean energy increased from 5.6 MeV to 6.4 MeV. The PDD was also increased by 2.77% when the energy spread increased from 0 MeV to 1.019 MeV. In the lateral dose profile, increasing the beam radial width from 0 mm to 4 mm at the full width at half maximum resulted in a dose decrease of 8.42% on the average. The profile also decreased by 4.81% when the mean energy was increased from 5.6 MeV to 6.4 MeV. Of all tested parameters, electron mean energy had the greatest influence on dose distribution. The PDD and profile were calculated using parameters optimized and compared with the golden beam data. The maximum dose difference was assessed as less than 2%. Conclusion: The relationship between the initial electron and treatment beam quality investigated in this study can be used in Monte Carlo commissioning of medical linear accelerator model.
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참고문헌 (21)
참고문헌 신청
Ma CM / 2000 / Monte Carlo verification of IMRT dose distributions from a commercial treatment planning optimization system / Phys. Med. Biol. 45(9):2483~2495
da Rosa LA / 2010 / Percentage depth dose evaluation in heterogeneous media using thermoluminescent dosimetry / J Appl. Clin. Med. Phys. 11(1):117~127
Sterpin E / 2007 / Monte Carlo evaluation of the AAA treatment planning algorithm in a heterogeneous multilayer phantom and IMRT clinical treatments for an Elekta SL25 linear accelerator / Medical Physics 34(5):1665~1677
Chetty IJ / 2007 / Report of the AAPM Task Group No. 105: Issues associated with clinical implementation of Monte Carlo-based photon and electron external beam treatment planning / Medical Physics 34(12):4818~4853
Verhaegen F / 2003 / Monte Carlo modelling of external radiotherapy photon beams / Phys. Med. Biol. 48(21):R107~R164
da Rosa LA / 2010 / Percentage depth dose evaluation in heterogeneous media using thermoluminescent dosimetry / J Appl. Clin. Med. Phys. 11(1):117~127
Sterpin E / 2007 / Monte Carlo evaluation of the AAA treatment planning algorithm in a heterogeneous multilayer phantom and IMRT clinical treatments for an Elekta SL25 linear accelerator / Medical Physics 34(5):1665~1677
Chetty IJ / 2007 / Report of the AAPM Task Group No. 105: Issues associated with clinical implementation of Monte Carlo-based photon and electron external beam treatment planning / Medical Physics 34(12):4818~4853
Verhaegen F / 2003 / Monte Carlo modelling of external radiotherapy photon beams / Phys. Med. Biol. 48(21):R107~R164
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