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자료유형
학술저널
저자정보
Safari, Somayyeh (Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences) Faramarzi, Azita (Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences) Agha-Rahimi, Azam (Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences) Khalili, Mohammad Ali (Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences)
저널정보
대한생식의학회 Clinical and experimental reproductive medicine : CERM Clinical and experimental reproductive medicine : CERM 제43권 제3호
발행연도
2016.1
수록면
181 - 184 (4page)

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The aim was to report a healthy live birth using re-vitrified-warmed cleavage-stage embryos derived from supernumerary warmed embryos after frozen embryo transfer (ET) in a patient with recurrent implantation failure (RIF). The case was a 39-year-old female with a history of polycystic ovarian syndrome and adenomyosis, along with RIF. After ovarian hyperstimulation, 33 cumulus-oocyte complexes were retrieved and fertilized with conventional in vitro fertilization and intracytoplasmic sperm injection. Because of the risk of ovarian hyperstimulation syndrome, 16 grade B and C embryos were vitrified. After 3 and 6 months, 3 and 4 B-C warmed embryos were transferred to the uterus, respectively. However, implantation did not take place. Ten months later, four embryos were warmed, two grade B 8-cell embryos were transferred, and two embryos were re-vitrified. One year later, the two re-vitrified cleavage-stage embryos were warmed, which resulted in a successful live birth. This finding showed that following first warming, it is feasible to refreeze supernumerary warmed embryos for subsequent ET in patients with a history of RIF.

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