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논문 기본 정보

자료유형
학술저널
저자정보
Yoon, Jeong (Maria Research Center) Yoon, Hye-Jin (Maria Fertility Hospital) Juhn, Kyoung-Mi (Maria Research Center) Ko, Jin-Kyung (Maria Research Center) Yoon, San-Hyun (Maria Research Center) Ko, Yong (Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University) Lim, Jin-Ho (Maria Fertility Hospital)
저널정보
대한생식의학회 Clinical and experimental reproductive medicine : CERM Clinical and experimental reproductive medicine : CERM 제38권 제4호
발행연도
2011.1
수록면
186 - 192 (7page)

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Objective: Since IVF program was first established, various types of media and culture systems have been developed either in-house or commercially. The aim of this study was to compare the efficacy of in-house Maria Research Center (MRC) media to that of commercially available Sydney IVF media in human day 3 embryo transfer cycles. Methods: Three hundred sixty nine couples were included in this prospective, randomized, and comparative study. All couples undergoing IVF treatment at the Maria Fertility Hospital were randomly assigned to either Sydney IVF (n=178) or MRC (n=191) media. Results: No difference was observed between the MRC media and Sydney IVF media groups with respect to fertilization rate (74.4% vs. 75.5%). The clinical pregnancy and implantation rates of MRC media (47.1% and 20.0%, respectively) were also similar to those of Sydney IVF media (44.4% and 19.4%, respectively). However, the proportion of embryos with good quality on day 3 was significantly higher in the MRC media group than the Sydney IVF media group (50.2% vs. 43.2%) ($p$ <0.05). Conclusion: MRC media were as effective as Sydney IVF media for sustaining embryo development and pregnancy rates. The present study implies that MRC media can be a suitable alternative to commercially available media for human IVF-ET program.

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