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논문 기본 정보

자료유형
학술저널
저자정보
Patarapadungkit, Natcha (Department of Pathology, Faculty of Medicine, Khon Kaen University) Koonmee, Supinda (Department of Pathology, Faculty of Medicine, Khon Kaen University) Pasatung, Emorn (Department of Pathology, Faculty of Medicine, Khon Kaen University) Pisuttimarn, Pornrith (Department of Medicine, Faculty of Medicine, Khon Kaen University) Mootsikapun, Piroon (Department of Medicine, Faculty of Medicine, Khon Kaen University)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제13권 제9호
발행연도
2012.1
수록면
4,487 - 4,490 (4page)

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This study aimed to screen for anal cancer and to determine its cytomorphology using liquid-based cytology (LBC) with specimens preserved in 95% ethyl alcohol. Anal swabs were collected for cytological examination from 177 adult, HIV-infected patients. After collection, sample slides were reviewed and classified according to their cytomorphology using the modified Bethesda 2001 system. An abnormal anal Pap smear was found in 26.0% of the patients. The diagnoses were: 66.7% negative for intraepithelial lesions (NIL), 14.1% with atypical squamous cells of undetermined significance (ASC-US), 10.7% (19) with low-grade squamous intraepithelial lesions (LSIL), and 1.13% with high-grade squamous intraepithelial lesions (HSIL). The cytological evaluation was an unsatisfactory result only with 6.67%. The present modified LBC using 95% ethyl alcohol as the preservative could thus be used for anal cancer screening. The number of SILs in Thai HIV-infected patients is lower than that in Western countries. We found anal cytology a satisfactory tool for early screening and detection of anal dysplasia commonly found in high-risk, HIV-infected patients.

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