Whole Brain Radiotherapy Combined with Stereotactic Radiosurgery versus Stereotactic Radiosurgery Alone for Brain Metastases

Adas, Yasemin Guzle; Yazici, Omer; Kekilli, Esra; Akkas, Ebru Atasever; Karakaya, Ebru; Ucer, Ali Riza; Ertas, Gulcin; Calikoglu, Tamer; Elgin, Yesim; Inan, Gonca Altinisik; Kocer, Ali Mert; Guney, Yildiz

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자료유형: 학술저널

저자정보: Adas, Yasemin Guzle (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Yazici, Omer (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Kekilli, Esra (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Akkas, Ebru Atasever (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Karakaya, Ebru (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Ucer, Ali Riza (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Ertas, Gulcin (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Calikoglu, Tamer (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Elgin, Yesim (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Inan, Gonca Altinisik (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Kocer, Ali Mert (Radiation Oncology Department, Ankara Oncology Training and Research Hospital) Guney, Yildiz (Radiation Oncology Department, Ankara Oncology Training and Research Hospital)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제16권 제17호

발행연도: 2015.1

수록면: 7,595 - 7,597 (3page)

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Background: The aim of this study was to evaluate the effect of whole brain radiotherapy (WBRT) combined with streotactic radiosurgery versus stereotactic radiosurgery (SRS) alone for patients with brain metastases. Materials and Methods: This was a retrospective study that evaluated the results of 46 patients treated for brain metastases at Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Radiation Oncology Department, between January 2012 and January 2015. Twenty-four patients were treated with WBRT+SRS while 22 patients were treated with only SRS. Results: Time to local recurrence was 9.7 months in the WBRT+SRS arm and 8.3 months in SRS arm, the difference not being statistically significant (p=0.7). Local recurrence rate was higher in the SRS alone arm but again without significance (p=0,06). Conclusions: In selected patient group with limited number (one to four) of brain metastases SRS alone can be considered as a treatment option and WBRT may be omitted in the initial treatment.

#Brain metastases #whole brain radiotherapy #stereotactic radiosurgery

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