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논문 기본 정보

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학술저널
저자정보
Ceylan, Seda (Department of Chemical Engineering, Mersin University) Demir, Didem (Department of Chemical Engineering, Mersin University) Gul, Gulsah (Department of Chemical Engineering, Mersin University) Bolgen, Nimet (Department of Chemical Engineering, Mersin University)
저널정보
테크노프레스 Biomaterials and Biomechanics in Bioengineering Biomaterials and Biomechanics in Bioengineering 제4권 제1호
발행연도
2019.1
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1 - 8 (8page)

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The aim of this study was to investigate the effect of total polymer concentration on the chemical structure, morphology of pores, porosity, swelling ratio, degradation of gelatin-poly (vinyl alcohol) (Gel-PVA) cryogel scaffolds. Porous cryogels were prepared with cryogelation technique by using glutaraldehyde as a crosslinker. Functional group composition of cryogels after crosslinking was investigated by Fourier Transform Infrared (FTIR). The morphology of cryogels was characterized via scanning electron microscopy (SEM) and porosity analysis. All of the cryogels had a porous structure with an average pore size between $45.58{\pm}14.28$ and $50.14{\pm}4.26{\mu}m$. The cryogels were biodegradable and started to degrade in 14 days. As the polymer concentration increased the swelling ratio, the porosity and the degradation rate decreased. Spongy and mechanically stable Gel-PVA cryogels, with tunable properties, can be potential candidates as scaffolds for tissue engineering applications.

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