지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 동향자료
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 18 - 25 (8page)
이용수
초록· 키워드
오류제보하기
In this study, graphene oxide(GO) was used as drug carriers to amorphize poorly watersoluble drugs via a co-spray drying process. Two poorly water-soluble drugs, fenofibrate and ibuprofen, were investigated. It was found that the drug molecules could be in the graphene nanosheets in amorphous or nano crystalline forms and thus have a significantly enhanced dissolution rate compared with the counterpart crystalline form. In addition, the dissolution of the amorphous drug enwrapped with the graphene oxide was higher than that of the amorphous drug in activated carbon (AC) even though the AC possessed a larger specific surface area than that of the graphene oxide. The amorphous formulations also remained stable under accelerated storage conditions ($40^{\circ}C$ and 75% relative humidity) for a study period of 14 months. Therefore, graphene oxide could be a potential drug carrier and amorphization agent for poorly water-soluble drugs to enhance their bioavailability.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Emerging Frontiers of Graphene in Biomedicine
Journal of Microbiology and Biotechnology
2015 .01
-
Fuctionalized graphene oxide and graphene bilayer structure for N-doped air stable field effect transistor
한국진공학회 학술발표회초록집
2015 .02
-
Electrical and magnetic properties of graphene/graphene oxide heterostructure
한국자기학회 학술연구발표회 논문개요집
2022 .05
-
Dry transfer method for CVD graphene using Water soluble inorganic compounds
한국진공학회 학술발표회초록집
2020 .02
-
Surface and Electrical Characterization of Electrochemically Oxidized Graphene
Applied Science and Convergence Technology
2019 .05
-
An Innovative Approach for Assessing Bioavailability of a Poorly Water-Soluble Drug Using Stable Isotope Tracer: HGR4113
한국분석과학회 학술대회
2023 .11
-
Fabrication of One-Dimensional Graphene Metal Edge Contact without Graphene Exfoliation
한국진공학회 학술발표회초록집
2016 .02
-
그래핀을 이용한 전자소자 연구
진공이야기
2016 .03
-
Electrical and magnetic properties of in-plane graphene/graphene oxide junction devices
한국자기학회 학술연구발표회 논문개요집
2021 .11
-
Surface engineered graphene-based photodetector using tungsten oxide supporting layer
한국진공학회 학술발표회초록집
2021 .02
-
Structural properties of reduced graphene oxides prepared using various reducing agents
Carbon letters
2015 .01
-
Review of the Direct Laser Synthesis of Functionalized Graphene and its Application in Sensor Technology
Applied Science and Convergence Technology
2019 .09
-
Protection of gold nanoparticles on concave surface structure while maintaining electron transparency using reduced or non-reduced graphene oxide layers
한국진공학회 학술발표회초록집
2017 .02
-
Mechanisms of Na adsorption on graphene and graphene oxide: density functional theory approach
Carbon letters
2015 .01
-
Spray coated 2D materials for Large area and Flexible Transparent Electrodes
한국진공학회 학술발표회초록집
2017 .02
-
Passivation effect of small molecules on graphene for high performance device applications
한국진공학회 학술발표회초록집
2015 .02
-
Recent Advances in the Low-Temperature Chemical Vapor Deposition Growth of Graphene
Applied Science and Convergence Technology
2022 .05
-
Colorimetric temperature measurement based on graphene oxide
한국진공학회 학술발표회초록집
2019 .08
-
Surface Condition and Conductance of Graphene in Redox Process
Applied Science and Convergence Technology
2021 .11
-
Influence of graphene-substrate interactions on the phonon excitations in graphene
한국진공학회 학술발표회초록집
2016 .08
이 논문의 저자 정보
최근 본 자료
댓글(0)
0