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학술저널
저자정보
Seto, Mika (Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Fukuoka University) Koga, Sayo (Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Fukuoka University) Kita, Ryosuke (Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Fukuoka University) Kikuta, Toshihiro (Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Fukuoka University)
저널정보
대한치과마취과학회 Journal of dental anesthesia and pain medicine Journal of dental anesthesia and pain medicine 제17권 제4호
발행연도
2017.1
수록면
323 - 327 (5page)

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QT prolongation is an electrocardiographic change that can lead to lethal arrhythmia. Acquired QT prolongation is known to be caused by drugs and electrolyte abnormalities. We report three cases in which the prolonged QT interval was improved at the time of operation by briefly discontinuing the drugs suspected to have caused the QT prolongation observed on preoperative electrocardiography. The QTc of cases 1, 2, and 3 improved from 518 to 429 ms, 463 to 441 ms, and 473 to 443 ms on discontinuing the use of a gastrointestinal prokinetic agent, a proton pump inhibitor, and a molecular targeted drug, respectively. These cases were considered to have drug-induced QT prolongation. We reaffirmed that even drugs administered for conditions unrelated to cardiac diseases can have adverse side effect of QT prolongation. In conclusion, our cases indicate that dental surgeons should be aware of the dangerous and even potentially lethal side effects of QT prolongation. For safe oral and maxillofacial surgery, cooperation with medical departments in various fields is important.

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