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학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

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논문 기본 정보

자료유형
학술저널
저자정보
Castel, Nikki (Department of Surgery, Division of Plastic Surgery, University of Hawai'i, John A. Burns School of Medicine) Soon-Sutton, Taylor (Department of Surgery, Division of Plastic Surgery, University of Hawai'i, John A. Burns School of Medicine) Deptula, Peter (Department of Surgery, Division of Plastic Surgery, University of Hawai'i, John A. Burns School of Medicine) Flaherty, Anna (Department of Surgery, Division of Plastic Surgery, University of Hawai'i, John A. Burns School of Medicine) Parsa, Fereydoun Don (Department of Surgery, Division of Plastic Surgery, University of Hawai'i, John A. Burns School of Medicine)
저널정보
대한성형외과학회 Archives of plastic surgery : APS Archives of plastic surgery : APS 제42권 제2호
발행연도
2015.1
수록면
186 - 193 (8page)

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Background Polyurethane coating of breast implants has been shown to reduce capsular contracture in short-term follow-up studies. This 30-year study is the longest examination of the use of polyurethane-coated implants and their correlation with capsular contracture. Methods This study evaluates the senior surgeon's (F.D.P.) experience with the use of polyurethane-coated implants in aesthetic breast augmentation in 382 patients over 30 years. Follow-up evaluations were conducted for six months after surgery. After the six-month follow-up period, 76 patients returned for reoperation. The gross findings, histology, and associated capsular contracture were noted at the time of explantation. Results No patient during the six-month follow-up period demonstrated capsular contracture. For those who underwent reoperation for capsular contracture, Baker II/III contractures were noted nine to 10 years after surgery and Baker IV contractures were noted 12 to 21 years after surgery. None of the explanted implants had macroscopic evidence of polyurethane, which was only found during the first five years after surgery. The microscopic presence of polyurethane was noted in all capsules up to 30 years after the original operation. Conclusions An inverse correlation was found between the amount of polyurethane coating on the implant and the occurrence of capsular contracture. Increasingly severe capsular contracture was associated with a decreased amount of polyurethane coating on the surface of the implants. No contracture occurred in patients whose implants showed incomplete biodegradation of polyurethane, as indicated by the visible presence of polyurethane coating. We recommend research to find a non-toxic, non-biodegradable synthetic material as an alternative to polyurethane.
#Polyurethanes #Implant capsular contracture #Breast implants

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참고문헌 (25)

참고문헌 신청
Ashley FL. / 1970 / A new type of breast prosthesis. Preliminary report / Plast Reconstr Surg 45:421~424 google schola U.S. Food and Drug Administration / FDA breast implant consumer handbook 2004: timeline of breast implant activities google schola Van Zele D / 2004 / Breast implants. A review / Acta Chir Belg 104:158~165 google schola National Toxicology Program / 1979 / Bioassay of 2,4-diaminotoluene for possible carcinogenicity / Natl Cancer Inst Carcinog Tech Rep Ser 162:1~139 google schola Pharma and MedTech Business Intellignece / The gray sheet: bristol-myers squibb polyurethane-coated breast implant study google schola

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