지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 631 - 640 (10page)
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초록· 키워드
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Milk oligosaccharides are the complex mixture of six monosaccharides namely, D-glucose, D-galactose, N-acetyl-glucosamine, N-acetyl-galactosamine, L-fucose, and N-acetyl-neuraminic acid. The mixture is categorized as neutral and acidic classes. Previously, 25 oligosaccharides in bovine milk and 115 oligosaccharides in human milk have been characterized. Because human intestine lacks the enzyme to hydrolyze the oligosaccharide structures, these substances can reach the colon without degradation and are known to have many health beneficial functions. It has been shown that this fraction of carbohydrate can increase the bifidobacterial population in the intestine and colon, resulting in a significant reduction of pathogenic bacteria. The role of milk oligosaccharides as a barrier against pathogens binding to the cell surface has recently been demonstrated. Milk oligosaccharides have the potential to produce immuno-modulation effects. It is also well known that oligosaccharides in milk have a significant influence on intestinal mineral absorption and in the formation of the brain and central nervous system. Due to its structural resemblance, bovine milk is considered to be the most potential source of oligosaccharides to produce the same effect of oligosaccharides present in human milk. This review describes the characteristics and potential health benefits of milk oligosaccharides as well as the prospects of oligosaccharides in bovine milk for use in functional foods.
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참고문헌 (79)
참고문헌 신청
Barile, D. / 2010 / Neutral and acidic oligosacchraridesin Hostein-Friesian colostrums during thefirst 3 days of lactation measured by high performance liquidchromatography on a microfluidic chip and time-of-flightmass spectrometry / J. Dairy Sci 93:3940~3949
Barile, D. / 2009 / Permeate from cheese wheyultrafiltration is a source of milk oligosaccharides / Int. DairyJ 19:524~530
Bode, L / 2006 / Recent advances on structure, metabolismand function of human milk oligosaccharides / J. Nutr 136:2127~2130
Bode, L. / 2004 / Inhibition of monocyte, lymphocyteand neutrophil adhesion to endothelial cells by humanmilk oligosaccharides / J. Throm. Haemost 92:1402~1410
Bode, L. / 2004 / Human milk oligosaccharides reduce platelet-neutrophilcomplex formation leading to a decrease in neutrophilbeta 2 integrin expression / J. Leukocyte Biol 76:820~826
Barile, D. / 2009 / Permeate from cheese wheyultrafiltration is a source of milk oligosaccharides / Int. DairyJ 19:524~530
Bode, L / 2006 / Recent advances on structure, metabolismand function of human milk oligosaccharides / J. Nutr 136:2127~2130
Bode, L. / 2004 / Inhibition of monocyte, lymphocyteand neutrophil adhesion to endothelial cells by humanmilk oligosaccharides / J. Throm. Haemost 92:1402~1410
Bode, L. / 2004 / Human milk oligosaccharides reduce platelet-neutrophilcomplex formation leading to a decrease in neutrophilbeta 2 integrin expression / J. Leukocyte Biol 76:820~826
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