지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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This study is executed to develop probiotics which produce S-adenosyl-L-methionine (SAM), a methyl group donor of the 5-methyltetrahydrofolate methylation reaction within the animal cell. SAM is an essential substance for the synthesis, activation, and metabolism of hormones, neurotransmitters, nucleic acids, phospholipids, and cell membranes of animals. The SAM is also known as a nutritional supplement to improve brain functions of the human. In this study, the SAM-producing strains are identified in 18 types of salted fish, and then, the strains with excellent SAM productions are being identified, with 1 strain in the Enterococcus genus and 9 strains in the Bacillus genus. Strains with a large amount of SAM production include the lactic acid bacteria such as En. faecium and En. durans, En. sanguinicola, as well as various strains in the Bacillus genus. The SAM-overproducing strains show antibacterial activities with certain harmful microbes in addition to the weak acid resistances and strong bile resistances, indicating characteristics of probiotics. It is possible that the jeotgal-originated beneficial strains with overproducing SAM can be commercially utilized in order to manufacture SAM enriched foods.
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등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Burren, K. A / 2006 / Quantitative analysis of S-adenosylmethionine and S-adenosyl-homocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry / J. Chromatogr. B 844:112~118
Cook, R. J / 1995 / Molecular mechanisms of defense by rhizobacteria against root disease / P. Natl. Acad. Sci. USA 92:4197~4201
Cooney, C. A / 1993 / Are somatic cells inherently deficient in methylation metabolism? A proposed mechanism for DNA methylation loss, senescence and aging / Growth Dev. Aging 57:261~273
Corrales, F / 1992 / S-adenosylmethionine treatment prevents carbon tetrachloride-induced S-adenosylmethionine synthetase inactivation and attenuates liver injury / Hepatology 16:1022~1027
Delgado, S / 2004 / Phenotypic and genetic diversity of Lactococcus lactis and Enterococcus spp. Strains isolated from Northern Spain starter-free farmhouse cheeses / Int. J. Food Microbiol 90:309~319
Cook, R. J / 1995 / Molecular mechanisms of defense by rhizobacteria against root disease / P. Natl. Acad. Sci. USA 92:4197~4201
Cooney, C. A / 1993 / Are somatic cells inherently deficient in methylation metabolism? A proposed mechanism for DNA methylation loss, senescence and aging / Growth Dev. Aging 57:261~273
Corrales, F / 1992 / S-adenosylmethionine treatment prevents carbon tetrachloride-induced S-adenosylmethionine synthetase inactivation and attenuates liver injury / Hepatology 16:1022~1027
Delgado, S / 2004 / Phenotypic and genetic diversity of Lactococcus lactis and Enterococcus spp. Strains isolated from Northern Spain starter-free farmhouse cheeses / Int. J. Food Microbiol 90:309~319
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