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논문 기본 정보

자료유형
학술저널
저자정보
Kang, Hyun-Gu (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) Kim, Ill-Hwa (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) Kim, Hyung-Jin (College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) Hwang, Dae-Yeon (Pusan National University Major of Biomaterials, School of Applied Life Science, College of Natural Resources & Life Science) Jee, Seung-Wan (Division of Laboratory Animal Resources, National Institute of Toxicological Research, KFDA) Noh, Gyu-Jin (College of Veterinary Medicine, Kyeongsang National University)
저널정보
한국동물번식학회 한국수정란이식학회지 한국수정란이식학회지 제23권 제2호
발행연도
2008.1
수록면
119 - 125 (7page)

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A 3-month-old American Cocker spaniel was presented at the Veterinary Teaching Hospital, Chungbuk National University, for examination of urinary tract after dissection of vaginal mass at local clinic before 10 days. Clinical examination of the affected bitch revealed a normal sized vulva in a normal anatomical position with a grossly enlarged clitoris, which contained an os clitoris. On examinations of the genital gland, there were testis, epididymis, ductus deferens and uterus. The histology of both gonads was primarily testis. Seminiferous tubules were divided into many parts by fibrous connective tissue. A small number of spermatogonia was present, but large numbers of Leydig's cells were existed. A normal female karyotype (78, XX) was detected in metaphase spreads obtained from cultured peripheral lymphocytes. Y chromosome specific sequences were not detected in genomic DNA by PCR. After 27 months, the os clitoris was larger than 3-month-old dog and os bone was more calcified than young age. Combining the results of cytogenetic, molecular genetic and histological examinations, the dog was diagnosed as a female hermaphrodite with Sry-negative XX sex reversal.

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