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논문 기본 정보

자료유형
학술저널
저자정보
Na Wang (Shandong University of Traditional Chinese Medicine) Xianlei Wang (National Oceanographic Cente) Mengjiao He (Shandong University of Traditional Chinese Medicine) Wenxiu Zheng (Shandong University of Traditional Chinese Medicine) Dongmei Qi (Shandong University of Traditional Chinese Medicine) Yongqing Zhang (Shandong University of Traditional Chinese Medicine) Chun-chao Han (Shandong University of Traditional Chinese Medicine)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.45 No.2
발행연도
2021.3
수록면
211 - 217 (7page)

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초록· 키워드

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The treatments of nervous system diseases (NSDs) have long been difficult issues for researchers because of their complexity of pathogenesis. With the advent of aging society, searching for effective treatments of NSDs has become a hot topic. Ginseng polysaccharides (GP), as the main biologically active substance in ginseng, has various biological properties in immune-regulation, anti-oxidant, anti-inflammation and etc. Considering the association between the effects of GP and the pathogenesis of neurological disorders, many related experiments have been conducted in recent years. In this paper, we reviewed previous studies about the effects and mechanisms of GP on diseases related to nervous system. We found GP play an ameliorative role on NSDs through the regulation of immune system, inflammatory response, oxidative damage and signaling pathway. Structure-activity relationship was also discussed and summarized. In addition, we provided new insights into GP as promising neuroprotective agent for its further development and utilization.

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ABSTRACT
1. Introduction
2. Compositions and structural characterization
3. Bioactivities
4. Effects of ginseng polysaccharides in nervous system diseases
5. Discussions
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