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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.3
- 수록면
- 40 - 40 (1page)
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초록· 키워드
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Introduction and Background
Stem cells are an effective method of biologic healing and can be used to enhance the natural enthesis of the tendon-to-bone junction in rotator cuff repair. This study investigated whether the application of engineered stem cell sheets using adipose-derived stem cells (ASCs) was effective in regenerating natural enthesis and, whether there was a difference in the result of repair depending on the applied location.
Material and Method
A chronic rotator cuff tear model was induced for 2 weeks, and rat ASC-derived cell sheets were transplanted into the tendon-to-bone junction during surgical repair. Based on the transplant location of the cell sheets, the difference in rotator cuff healing level between the overlay group and the interposition group was compared with the surgical repair only group. The samples were obtained based on the tendon-to-bone junction, and analysis of gross morphology, histology staining, and biomechanical analysis were performed.
Results
The differenti^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10566529');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
Stem cells are an effective method of biologic healing and can be used to enhance the natural enthesis of the tendon-to-bone junction in rotator cuff repair. This study investigated whether the application of engineered stem cell sheets using adipose-derived stem cells (ASCs) was effective in regenerating natural enthesis and, whether there was a difference in the result of repair depending on the applied location.
Material and Method
A chronic rotator cuff tear model was induced for 2 weeks, and rat ASC-derived cell sheets were transplanted into the tendon-to-bone junction during surgical repair. Based on the transplant location of the cell sheets, the difference in rotator cuff healing level between the overlay group and the interposition group was compared with the surgical repair only group. The samples were obtained based on the tendon-to-bone junction, and analysis of gross morphology, histology staining, and biomechanical analysis were performed.
Results
The differenti^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10566529');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
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