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저자정보
(Hallym University) (Soonchunhyan University) (Yonsei University) (Korea Basic Science Institute) (University of Ulsan College of Medicine) (Hallym University)
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한국미생물학회 한국미생물학회 학술대회논문집 2020년도 ANNUAL MEETING OF THE MICROBIOLOGICAL SOCIETY OF KOREA
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    초록·키워드

    Pseudomonas aeruginosa, an opportunistic human pathogen experiences a big change in temperature during infection into human body. In this study, we investigated the temperature effect on the biofilm formation of P. aeruginosa and revealed that the biofilm formation increased rapidly at temperatures lower than 25°C. P. aeruginosa formed the most robust biofilm of conspicuous mushroom-like structure at 20°C. However, when the temperature increased to 25°C, the biofilm formation rapidly decreased. Above 25°C, as the temperature rose, the biofilm formation increased again little by little despite its less structured form, indicating that 25°C was the low point of biofilm formation. When the intracellular c-di-GMP levels were measured with temperature, it decreased rapidly as the temperature rose from 20 to 25°C, and there was no significant change above 25°C. The expression of pel, alg, and psl genes encodin ... 전체 초록 보기

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