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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 62 - 62 (1page)
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Due to recent clinical success in radioligand therapy, represented by Lu-177 DOTATATE therapy, a new theranostics agent has been suggested and clinical trials are increasing. Radioligand therapy expands to metastatic castration resistance prostate cancer by targeting PSMA as a phase III trial for Lu-177 PSMA-617 achieves the survival gain, as a primary endpoint. Radioligand therapy has many advantages in drug platforms targeting specific molecules. Especially, animal models with molecular imaging facilitate the development of new theranostic agents. As a preclinical study, animal molecular imaging provides pharmacokinetic information directly. Because therapeutic efficacy and toxicity of radionuclide depends on radiation dose instead of pharmacodynamics. Therefore, animal molecular imaging provides an informatio ... 전체 초록 보기
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