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(Chungbuk National University) (Chungbuk National University) (Chungbuk National University) (Chungbuk National University) (Designed Cells) (Chungbuk National University) (Chungbuk National University) (Designed Cells) (Chungbuk National University) (Chungbuk National University)
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한국실험동물학회 한국실험동물학회 학술발표대회 논문집 2021년 한국실험동물학회 국제학술대회 [초록집]
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    초록·키워드

    In modern society, baldness might be one of the hot social issues, beyond the individual"s seriously-depressing problem. Keratinocyte growth factor (KGF) is a key factor for the growth of germinal matrix and differentiation. Platelet rich plasma (PRP) was reported to play an important role in angiogenesis and activation of principal cells in the skin. We established human neural stem cells (NSC) encoding KGF gene (named NSC.KGF), and collected exosome-rich conditioned medium (ERCM) was collected after 24-hour hypoxic (2% O2) culture of NSC.KGF. The hair growth-enhancing activities of stem cells and ERCM were assessed, in comparison with PRP. After shaving the backside of male C57BL/6 mice, NSC (104 cells/200 μL), NSC.KGF (104 cells/200 μL), ERCM (200 μL) or PRP (200 μL) was subcutaneo ... 전체 초록 보기

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