인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 저자정보
피인용 0
초록·키워드
This review attempts to examine the relationships between chronic low-grade inflammation and aging processes. Inflammation plays a critical role in the host defence against various microorganisms and pathogens. However, chronic low-level inflammation is associated with various aging processes. Older persons tend to exhibit a pro-inflammatory state. Various variables including genetic factors and the behavioral & environmental circumstances, can have a strong effect on inflammatory cytokines, which is likely to accelerate chronic diseases and aging. Chronic low-grade inflammation may make individuals more prone to developing age-related chronic diseases. Therefore, the aging process can be determined by the outcome of the balance between inflammatory and anti-inflammatory mediators. Autophagy has critical effects on the initiation and regulation of inflammatory reaction. This suggests that understanding the balance between inflammasome activation and autophagy is important to determine therapeutic targeting. Caloric restriction is associated with positive effect as key interventions in the regulations and attenuations of aging processes, DNA damages, inflammatory processes, and age-related disorders. This suggests that the proper regulation of inflammation by caloric restriction in aging can be a major target for the strategies of anti-inflamm-aging remodelling.
본문·목차
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오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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