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논문 기본 정보

자료유형
학술저널
저자정보
Naoyuki Takashima (Department of Public Health Shiga University of Medical Science Otsu Japan) Hisatomi Arima (Fukuoka University Faculty of Medicine Fukuoka Japan) Yoshikuni Kita (Department of Public Health Shiga University of Medical Science Otsu Japan) Takako Fujii (Fukuoka University Faculty of Medicine Fukuoka Japan) Sachiko Tanaka-Mizuno (Department of Medical Statistics Shiga University of Medical Science Otsu Japan) Satoshi Shitara (Department of Neurosurgery Shiga University of Medical Science Otsu Japan) Akihiro Kitamura (Department of Neurology Shiga University of Medical Science Otsu Japan) Yoshihisa Sugimoto (Shiga University of Medical Science Otsu Japan) Makoto Urushitani (Department of Neurology Shiga University of Medical Science Otsu Japan) Katsuyuki Miura (Department of Public Health Shiga University of Medical Science Otsu Japan) Kazuhiko Nozaki (Department of Neurosurgery Shiga University of Medical Science Otsu Japan)
저널정보
대한뇌졸중학회 대한뇌졸중학회지 대한뇌졸중학회지 제22권 제3호
발행연도
2020.1
수록면
336 - 344 (9page)

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Background and Purpose Although numerous measures for stroke exist, stroke remains one of the leading causes of death in Japan. In this study, we aimed to determine the long-term survival rate after first-ever stroke using data from a large-scale population-based stroke registry study in Japan. Methods Part of the Shiga Stroke and Heart Attack Registry, the Shiga Stroke Registry is an ongoing population-based registry study of stroke, which covers approximately 1.4 million residents of Shiga Prefecture in Japan. A total 1,880 patients with non-fatal first-ever stroke (among 29-day survivors after stroke onset) registered in 2011 were followed up until December 2016. Five-year cumulative survival rates were estimated using the Kaplan-Meier method, according to subtype of the index stroke. Cox proportional hazards models were used to assess predictors of subsequent allcause death. Results During an average 4.3-year follow-up period, 677 patients died. The 5-year cumulative survival rate after non-fatal first-ever stroke was 65.9%. Heterogeneity was present in 5-year cumulative survival according to stroke subtype: lacunar infarction, 75.1%; large-artery infarction, 61.5%; cardioembolic infarction, 44.9%; intracerebral hemorrhage, 69.1%; and subarachnoid hemorrhage, 77.9%. Age, male sex, Japan Coma Scale score on admission, and modified Rankin Scale score before stroke onset were associated with increased mortality during the chronic phase of ischemic and hemorrhagic stroke. Conclusions In this study conducted in a real-world setting of Japan, the 5-year survival rate after non-fatal first-ever stroke remained low, particularly among patients with cardioembolic infarction and large-artery infarction in the present population-based stroke registry.

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