지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 458 - 465 (8page)
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초록· 키워드
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Background/Aims: Endoscopic treatment (ET) has been applied for decades to treat subepithelial tumors, including gastrointestinalstromal tumors (GISTs). However, the effcacy of ET remains debatable. In this study, we evaluated the effcacy and safety of ET forGISTs in the upper gastrointestinal tract. Methods: This retrospective single-center study included 97 patients who underwent ET. All patients were enrolled from July 2014 toJuly 2018. Parameters such as demographics, size, resection margin, complications, pathological features, procedure time, total cost, andfollow-up were investigated and analyzed. Results: Our study achieved 100% en bloc resection and 77.4% (72/93) R0 resection. The most common location was the funduswith a mean tumor size of 2.1±1.4 cm. The mean age, procedure time, hospital stay, and cost were 59.7±11.3 years, 64.7±35.2 minutes,6.8 days, and 5,337 dollars, respectively. According to National Institutes of Health classification, 63 (64.9%), 26 (26.8%), 5 (5.2%), and3 (3.1%) patients belonged to the very low, low, intermediate, and high risk classification, respectively. Immunohistochemistry resultsshowed a 100% positive rate of CD34, DOG-1, CD117, and Ki67. A mean follow-up of 21.3±13.0 months showed no recurrence ormetastasis. Conclusions: ET is effective and safe for curative removal of GISTs in the upper gastrointestinal tract, and it can be a treatment ofchoice for patients with no metastasis.
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참고문헌 (41)
참고문헌 신청
Nilsson B / 2005 / Gastrointestinal stromal tumors : the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era--a population-based study in western Sweden / Cancer 103:821~829
Alvarado-Cabrero I / 2007 / Clinicopathologic study of 275 cases of gastrointestinal stromal tumors : the experience at 3 large medical centers in Mexico / Ann Diagn Pathol 11:39~45
Ankit Chhoda / 2018 / Contrast Enhanced Harmonic Endoscopic Ultrasound: A Novel Approach for Diagnosis and Management of Gastrointestinal Stromal Tumors / Clinical Endoscopy 51(3):215~221
Fletcher CD / 2002 / Diagnosis of gastrointestinal stromal tumors : a consensus approach / Int J Surg Pathol 10:81~89
ESMO/European Sarcoma Network Working Group / 2014 / Gastrointestinal stromal tumours: ESMO clinical practice guidelines for diagnosis, treatment and follow-up / Ann Oncol 25(Suppl 3):iii21~iii26
Alvarado-Cabrero I / 2007 / Clinicopathologic study of 275 cases of gastrointestinal stromal tumors : the experience at 3 large medical centers in Mexico / Ann Diagn Pathol 11:39~45
Ankit Chhoda / 2018 / Contrast Enhanced Harmonic Endoscopic Ultrasound: A Novel Approach for Diagnosis and Management of Gastrointestinal Stromal Tumors / Clinical Endoscopy 51(3):215~221
Fletcher CD / 2002 / Diagnosis of gastrointestinal stromal tumors : a consensus approach / Int J Surg Pathol 10:81~89
ESMO/European Sarcoma Network Working Group / 2014 / Gastrointestinal stromal tumours: ESMO clinical practice guidelines for diagnosis, treatment and follow-up / Ann Oncol 25(Suppl 3):iii21~iii26
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