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논문 기본 정보

자료유형
학술저널
저자정보
Jung Hye-Kyung (Department of Internal Medicine Ewha Womans University School of Medicine Seoul Korea) Kang Seung Joo (Department of Internal Medicine Seoul National University Hospital Gangnam Center Seoul Korea) Lee Yong Chan (Department of Internal Medicine Yonsei University College of Medicine Seoul Korea) Yang Hyo-Joon (Division of Gastroenterology Department of Internal Medicine and Gastrointestinal Cancer Center Kan) Park Seon-Young (Department of Internal Medicine Chonnam National University Medical School Gwangju Korea) Shin Cheol Min (Department of Internal Medicine Seoul National University Bundang Hospital Seongnam KoreaDepartment) Kim Sung Eun (Department of Internal Medicine Kosin University College of Medicine Busan Korea) Lim Hyun Chul (Department of Internal Medicine Yongin Severance Hospital Yonsei University College of Medicine Yon) Kim Jie-Hyun (Department of Internal Medicine and Institute of Gastroenterology Yonsei University College of Medi) Nam Su Youn (Center for Gastric Cancer Kyungpook National University Hospital Chilgok Hospital School of Medicin) Shin Woon Geon (Department of Internal Medicine Hallym University College of Medicine Seoul Korea) Park Jae Myung (Division of Gastroenterology and Hepatology Department of Internal Medicine Seoul St. Mary’s Hospit) Choi Il Ju (Center for Gastric Cancer National Cancer Center Goyang Korea) Kim Jae Gyu (Department of Internal Medicine Chung-Ang University College of Medicine Seoul Korea) Choi Miyoung (Division of Healthcare Technology Assessment Research National Evidence-based Healthcare Collaborat)
저널정보
거트앤리버 발행위원회 Gut and Liver Gut and Liver 제15권 제2호
발행연도
2021.1
수록면
168 - 195 (28page)

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초록· 키워드

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Helicobacter pylori infection is one of the most common infectious diseases worldwide. Although the prevalence of H. pylori is gradually decreasing, approximately half of the world's population still becomes infected with this disease. H. pylori is responsible for substantial gastrointestinal morbidity worldwide, with a high disease burden. It is the most common cause of gastric and duodenal ulcers and gastric cancer. Since the revision of the H. pylori clinical practice guidelines in 2013 in Korea, the eradication rate of H. pylori has gradually decreased with the use of a clarithromycin-based triple therapy for 7 days. According to a nationwide randomized controlled study conducted by the Korean College of Helicobacter and Upper Gastrointestinal Research released in 2018, the intention-to-treat eradication rate was only 63.9%, which was mostly due to increased antimicrobial resistance, especially from clarithromycin. The clinical practice guidelines for the treatment of H. pylori were updated according to evidence-based medicine from a meta-analysis conducted on a target group receiving the latest level of eradication therapy. The draft recommendations developed based on the meta-analysis were finalized after an expert consensus on three recommendations regarding the indication for treatment and eight recommendations for the treatment itself. These guidelines were designed to provide clinical evidence for the treatment (including primary care treatment) of H. pylori infection to patients, nurses, medical school students, policymakers, and clinicians. These may differ from current medical insurance standards and will be revised if more evidence emerges in the future.
#Helicobacter pylori #Guidelines #Treatment #Meta-analysis #Microbial sensitivity tests

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