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논문 기본 정보

자료유형
학술저널
저자정보
Ara Cho (Seoul National University College of Medicine) Jeong-Moo Lee (Seoul National University College of Medicine) Kwangpyo Hong (Seoul National University College of Medicine) Eui Soo Han (Seoul National University College of Medicine) Suk Kyun Hong (Seoul National University College of Medicine) YoungRok Choi (Seoul National University College of Medicine) Nam-Joon Yi (Seoul National University College of Medicine) Kwang-Woong Lee (Seoul National University College of Medicine) Kyung-Suk Suh (Seoul National University College of Medicine)
저널정보
한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제25권 제4호
발행연도
2021.11
수록면
551 - 555 (5page)

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Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare delayed-type hypersensitivity reaction that causes skin abnormalities and mucosal involvement of the entire body. This is a case report of DRESS occurring in a liver transplantation recipient after taking drugs. A 57-year-old female patient with hepatocellular carcinoma underwent living donor liver transplantation in April 2019. She had no previous medical histories relevant to allergic diseases. There were no adverse events during hospitalization. She was admitted to evaluate and treat a headache occurring at one month after transplantation. However, she suffered from adverse drug reactions after taking anticonvulsants, showing skin rash, itching sense, and fever with eosinophilia. Piperacillin/Tazoperan was administered for ten days as an empirical antibiotic. Skin biopsy was performed on postoperative day 106 for erythematous maculopapular rash in the arms, legs, and torso. Her symptoms improved after discontinuation of the suspected medication with conservative skin treatment and high-dose steroid treatment. This case suggests that suspicion of drug history is essential for early diagnosis and management of DRESS.

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