지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 340 - 340 (1page)
이용수
초록· 키워드
오류제보하기
microRNAs (miRs) are short non-coding RNAs that bind to the 3’untranslated regions of target mRNA and usually inhibit protein expression through RNA interference. The miRs targeting insulin signaling molecules have been reported to participate actively in the pathogenesis of hepatic IR. Phenolic acids are widely found in daily foods such as cereals, legumes, fruits, and vegetables and they provide medicinal and biological properties. However, it is not clear whether phenolic acids play any role in the hepatic insulin signaling pathway through the regulation of miRs expression. This study investigated miR profile to confirm the function of phenolic acids and examined the role of phenolic acids and miRs in insulin signaling pathway. A total of 69 significantly differentially expressed miRs was investigated. Prediction and validation of miRs associated with insulin resistance were implemented by TargetScan and qRT-PCR. Glucose consumption, reactive oxygen species (ROS) production, and miRs expression, as well as protein levels of p-IRS, p-PI3K, p-AKT, and p-FOXO1 were analyzed. Furthermore, miR-1271 mimic or inhibitor transfection was executed to explore the possible mechanisms of phenolic acids in cellular studies. Phenolic acids enhanced gl^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10668423');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Identification and expression analysis of SQUAMOSA promoter-binding protein (SBP) genes in mungbean
Plant Biotechnology Reports
2023 .06
-
MicroRNA expression profiling during the suckling-to-weaning transition in pigs
한국축산학회지
2021 .01
-
Antioxidant enzyme activity and microRNA are associated with growth of Poa pratensis callus under salt stress
Plant Biotechnology Reports
2020 .01
-
MicroRNA gga-miR-10a modulates Toll-like receptor signaling pathway via regulation of MyD88
한국가금학회 정기총회 및 학술발표회
2020 .11
-
HB31 and HB21 regulate floral architecture through miRNA396/GRF modules in Arabidopsis
Plant Biotechnology Reports
2024 .02
-
Stability of phenolic acids and the effect on weed control activity
Applied Biological Chemistry
2015 .01
-
miR-200a-3p regulates immune response in necrotic enteritis-afflicted chickens
한국가금학회 정기총회 및 학술발표회
2022 .11
-
MiR-141 is Associated with the Mitochondrial Dysfunction in Skeletal Muscle of Ovariectomized Mice
한국식품영양과학회 학술대회발표집
2019 .10
-
Investigating effect of miR160 through overexpression in potato cultivars under single or combination of heat and drought stresses
Plant Biotechnology Reports
2021 .01
-
MIR 근접토양센싱 기법 활용 한국 토양특성 예측 방법 개발
한국토양비료학회 학술발표회 초록집
2022 .10
-
몽골산 Iris bungei 추출물의 자유 라디칼 소거 및 α-glucosidase 저해 활성
Food Science and Preservation
2017 .10
-
Responses of the phenolic compounds of Zea mays under heavy metal stress
Applied Biological Chemistry
2016 .01
-
Selected Phenolics for Health Management
한국식품영양과학회 학술대회발표집
2015 .08
-
Phenolic acids의 항산화 및 항당뇨 활성 비교
한국식품영양과학회 학술대회발표집
2020 .10
-
Comparative study of the Structure and Antioxidant Activity of Protocatechuic Acid and Phenolic Acid Derivatives
한국식품영양과학회 학술대회발표집
2016 .10
-
Effects of Quercetin Nanoemulsion on Cholesterol Efflux and MicroRNA-33/34a Expression in the Liver of Mice Fed with a High-Cholesterol Diet
Preventive Nutrition and Food Science
2023 .09
-
Single nucleotide polymorphism in the seed region of btamiR- 2468 and its binding to a specific-site within the 3’UTR of GPAM in Korean Native cattle
Journal of Animal Breeding and Genomics
2022 .09
-
β-laphachone attenuates Adipogenesis via Regulation of miR-494 Targeting ATF3
한국식품영양과학회 학술대회발표집
2015 .08
-
인간 대장암 세포주에서 miR-20b-5p 조절을 통한 1,2,3,4,6-penta-O-Galloyl-β-D-glucose의 세포사멸 효과
한국식품영양과학회 학술대회발표집
2022 .10
-
Profiles of Phenolic Acids and Amino Acids from Stevia Extracts Obtained by Optimized Heat-Reflux Method
한국식품영양과학회 학술대회발표집
2017 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0