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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 1 - 13 (13page)
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초록· 키워드
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Background: Individual particulate respirator use may offer protection against exposure to particulate matter < 2.5 µm in diameter (PM2.5). Among elderly Korean women, we explored individual particulate respirator use and cardiopulmonary function. Methods: Recruited in Seoul, Korea, 21 elderly, non-smoking women wore particulate respirators for six consecutive days (exlcuding time spent eating, sleeping, and bathing). We measured resting blood pressure before, during, and after respirator use and recorded systolic and diastolic blood pressure, mean arterial blood pressure, pulse pressure, and lung function. We also measured 12-hour ambulatory blood pressure at the end of the 6-day long experiment and control periods. Additionally, we examined physiological stress (heart rate variability and urinary 8-hydroxy-2′-deoxyguanosine) while wearing the particulate respirators. Person- and exposure-level covariates were also considered in the model. Results: After the 6-day period of respirator use, resting blood pressure was reduced by 5.3 mmHg for systolic blood pressure (P = 0.013), 2.9 mmHg for mean arterial blood pressure (P = 0.079), and 3.6 mmHg for pulse pressure (P = 0.024). However, particulate respirator use was associated with changes in physiological stress markers. A parasympathetic activity marker (high frequency) significantly decreased by 24.0% (P = 0.029), whereas a sympathetic activity marker (ratio of low-to-high frequency) increased by 50.3% (P = 0.045). An oxidative stress marker, 8-hydroxy-2′-deoxyguanosine, increased by 3.4 ng/mg creatinine (P = 0.021) during the experimental period compared with that during the control period. Lung function indices indicated that wearing particulate respirators was protective; however, statistical significance was not confirmed. Conclusion: Individual particulate respirator use may prevent PM2.5-induced blood-pressure elevation among elderly Korean women. However, the effects of particulate respirator use, including physiological stress marker elevation, should also be considered.
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참고문헌 (41)
참고문헌 신청
Cohen AJ / 2017 / Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution : an analysis of data from the Global Burden of Diseases Study 2015 / Lancet 389(10082):1907~1918
Wang C / 2015 / PM2. 5 and cardiovascular diseases in the elderly : an overview / Int J Environ Res Public Health 12(7):8187~8197
박해용 / 2019 / The Effects of PM10 on the Hospital Admission of Patients with Respiratory Disease in Seoul, Korea / 융합정보논문지 9(6):194~201
Delfino RJ / 2010 / Traffic-related air pollution and blood pressure in elderly subjects with coronary artery disease / Epidemiology 21(3):396~404
Hoffmann B / 2012 / Opposing effects of particle pollution, ozone, and ambient temperature on arterial blood pressure / Environ Health Perspect 120(2):241~246
Wang C / 2015 / PM2. 5 and cardiovascular diseases in the elderly : an overview / Int J Environ Res Public Health 12(7):8187~8197
박해용 / 2019 / The Effects of PM10 on the Hospital Admission of Patients with Respiratory Disease in Seoul, Korea / 융합정보논문지 9(6):194~201
Delfino RJ / 2010 / Traffic-related air pollution and blood pressure in elderly subjects with coronary artery disease / Epidemiology 21(3):396~404
Hoffmann B / 2012 / Opposing effects of particle pollution, ozone, and ambient temperature on arterial blood pressure / Environ Health Perspect 120(2):241~246
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