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논문 기본 정보

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학술저널
저자정보
Kim Minkwan (Division of Cardiology Department of Internal Medicine Yongin Severance Hospital Yonsei University) Nam Jong-Ho (Division of Cardiology Department of Internal Medicine Yeungnam University Medical Center Daegu Kor) Son Jang-Won (Division of Cardiology Department of Internal Medicine Yeungnam University Medical Center Daegu Kor) Kim Sun Oh (Department of Internal Medicine Yeungnam University Medical Center Daegu Korea.) Son Nak-Hoon (Data Science Team(Biostatistician) Center for Digital Health Yongin Severance Hospital Yonsei Unive) Ahn Chul-Min (Division of Cardiology Department of Internal Medicine Severance Hospital Yonsei University College) 심지영 (연세대학교) 홍그루 (연세대학교) Kim In-Cheol (Division of Cardiology Department of Internal Medicine Cardiovascular Center Keimyung University Do) Choi Jinwoo (Chungju Medical Center Chungju Korea.) Kang Seung-Mo (Chungju Medical Center Chungju Korea.) Choi Yeoung Ho (Chungju Medical Center Chungju Korea.) Yoon Hae Kyoung (Chungju Medical Center Chungju Korea.) 엄재선 (연세대학교) 정인현 (연세대학교)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.35 No.40
발행연도
2020.1
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1 - 13 (13page)

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Background: This study aimed to investigate the cardiac manifestations of coronavirus disease 2019 (COVID-19). Methods: From February to March 2020, we prospectively and retrospectively enrolled consecutive patients diagnosed with COVID-19. Patient's data such as the demographic characteristics, symptoms, vital signs, laboratory and radiologic findings, electrocardiographic, and echocardiographic data, including the global longitudinal strain (GLS) of both ventricles, were obtained. Results: Forty patients (median age, 58 years; 50% men) were enrolled in the initial analysis. Patients were classified into severe and nonsevere groups based on the current guidelines. The 13 patients in the severe group were significantly older, had a greater prevalence of bilateral pneumonia and leukocytosis, and higher aspartate transaminase levels than patients in the nonsevere group. Patients in the severe group had a slightly lower left ventricular ejection fraction (LVEF) than those in the nonsevere group (median [interquartile range], 61.0% [58.5%, 62.3%] vs. 66.7% [60.6%, 69.8%], P = 0.015). In a subgroup of 34 patients in whom GLS could be analyzed, patients in the severe group had a significantly impaired left ventricular GLS (LVGLS) than those in the nonsevere group (−18.1% [−18.8%, −17.1%] vs. −21.7% [−22.9%, −19.9%], P = 0.001). There were no significant differences in total wall (RVGLStotal, −19.3% [−23.9%, −18.4%] vs. −24.3% [−26.0%, −22.6%], P = 0.060) and free wall (RVGLSfw, −22.7% [−27.2%, −18.6%] vs. −28.8% [−30.4%, −24.1%], P = 0.066) right ventricle GLS (RVGLS). Conclusion: Patients with severe COVID-19 had lower LVEF and LVGLS. RVGLS was not different between patients with severe and nonsevere COVID-19.
#Coronavirus #COVID-19 #Echocardiography #Global Longitudinal Strain #Ejection Fraction #Disease Severity

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참고문헌 (27)

참고문헌 신청
Lu R / 2020 / Genomic characterisation and epidemiology of 2019 novel coronavirus : implications for virus origins and receptor binding / Lancet 395(10224):565~574 google schola World Health Organization / 2020 / Coronavirus Disease (COVID-2019) Situation Report-107 google schola Guan WJ / 2020 / Clinical characteristics of coronavirus disease 2019in China / N Engl J Med 382(18):1708~1720 google schola Deng SQ / 2020 / Characteristics of and public health responses to the coronavirus disease 2019outbreak in China / J Clin Med 9(2):575 google schola Mehra MR / 2020 / Cardiovascular disease, drug therapy, and mortality in COVID-19 / N Engl J Med 382(26):2582 google schola

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