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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 669 - 682 (14page)
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초록· 키워드
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Porous materials were developed as a good alternative to replace different bones in the human body as they improve osseointegration,tissue ingrowth and simulate the mechanical properties of human bones. Such characteristics highly depend on thepore features and volume fraction. Samples with a pore volume fraction between 16 and 60% and a pore size distribution of100–500 μm were analyzed by computed microtomography. 3D images acquisition was performed at 10 μm pixel resolution,which permitted to observe the complete sample. Features like size, shape, orientation, connectivity and pore coordinationwere determined from the 3D image analysis. Compression behavior was evaluated by interrupted compression testing and,after that, new 3D images were acquired. In order to evaluate permeability, numerical simulations of flow throughout the3D images were carried out by using Avizo® software. It was found that shape and pore size distribution was similar in allsamples, showing good distribution of the pore formers inside the matrix. Full connectivity of pores was obtained with 32%volume fraction and above, and the coordination number follows the Artz model. The pores showed a radial orientation,which induces anisotropy in the flow properties. The compression showed two different behaviors, pore closing and porecoalescence. Values of permeability match with those reported for bones as well as the anisotropy in the radial and verticaldirections. It is concluded that the sample with 60 vol% of pores could be consider to be used for bone implants.
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참고문헌 (45)
참고문헌 신청
Xiaojian Wang / 2016 / Topological design and additive manufacturing of porous metals for bone scaffolds and orthopaedic implants: A review / Biomaterials 83:127~141
L.E. Murr / 2012 / Int. J. Biomater
Qizhi Z. Chen / 2006 / 45S5 Bioglass®-derived glass–ceramic scaffolds for bone tissue engineering / Biomaterials 27(11):2414~2425
Brett Russell Levine / 2006 / Experimental and clinical performance of porous tantalum in orthopedic surgery / Biomaterials 27(27):4671~4681
Félix A. España / 2010 / Design and fabrication of CoCrMo alloy based novel structures for load bearing implants using laser engineered net shaping / Materials Science and Engineering: C 30(1):50~57
L.E. Murr / 2012 / Int. J. Biomater
Qizhi Z. Chen / 2006 / 45S5 Bioglass®-derived glass–ceramic scaffolds for bone tissue engineering / Biomaterials 27(11):2414~2425
Brett Russell Levine / 2006 / Experimental and clinical performance of porous tantalum in orthopedic surgery / Biomaterials 27(27):4671~4681
Félix A. España / 2010 / Design and fabrication of CoCrMo alloy based novel structures for load bearing implants using laser engineered net shaping / Materials Science and Engineering: C 30(1):50~57
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