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자료유형
학술저널
저자정보
윤경진 (Yeouido St. Mary’s Hospital College of Medicine The Catholic University of Korea) 하정훈 (가톨릭대학교) 김민희 (가톨릭의대부속여의도성모병원) 서예영 (인제대학교부속상계백병원) 김미경 (가톨릭대학교) 권혁상 (가톨릭대학교) 송기호 (가톨릭대학교 여의도성모병원 내과) 강무일 (가톨릭대학교) 백기현 (가톨릭대학교)
저널정보
대한내분비학회 Endocrinology and Metabolism Endocrinology and Metabolism Vol.34 No.2
발행연도
2019.1
수록면
195 - 202 (8page)

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Background: The natural course of thyroid cancer nodules and benign nodules is different. This study was to compare the changesin size between thyroid cancer nodules and thyroid benign nodules. The risk factors associated with the changes of thyroid cancernodules were assessed. Methods: This study contains retrospective observational and prospective analysis. A total of 113 patients with 120 nodules were recruited in the cancer group, and 116 patients with 119 nodules were enrolled in the benign group. Thyroid ultrasonography was performed at least two times at more than 1-year interval. Results: The mean follow-up durations were 29.5±18.8 months (cancer group) and 31.9±15.8 months (benign group) (P=0.32). The maximum diameter change in length was 0.36±0.97 mm/year in the cancer group and –0.04±0.77 mm/year in the benigngroup (P<0.01). The volume was significantly increased in the cancer group compared with the benign group (0.06±0.18 mL/yearvs. 0.004±0.05 mL/year, respectively, P<0.01; 26.9%±57.9%/year vs. 1.7%±26.0%/year, P<0.01). Initial maximum diameter(β=0.02, P<0.01) and initial volume (β=0.13, P<0.01) were significantly associated with volume change (mL)/year. Initial maximum standardized uptake value did not predict the nodule growth. Conclusion: It is suggested that thyroid cancer nodules progress rapidly compared with benign nodules. Initial size and volume ofnodule were independent risk factors for cancer nodule growth.

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