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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 91 - 111 (21page)
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Cardiovascular disease (CVD) is considered a primary driver of global mortality and is estimated to be responsible for approximately 17.9 million deaths annually. Consequently, a substantial body of research related to CVD has developed, with an emphasis on identifying strategies for the prevention and effective treatment of CVD. In this review, we critically examine the existing CVD literature, and specifically highlight the contribution of Mendelian randomization analyses in CVD research. Throughout this review, we assess the extent to which research findings agree across a range of studies of differing design within a triangulation framework. If differing study designs are subject to non-overlapping sources of bias, consistent findings limit the extent to which results are merely an artefact of study design. Consequently, broad agreement across differing studies can be viewed as providing more robust causal evidence in contrast to limiting the scope of the review to a single specific study design. Utilising the triangulation approach, we highlight emerging patterns in research findings, and explore the potential of identified risk factors as targets for precision medicine and novel interventions.
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참고문헌 (142)
참고문헌 신청
Benjamin EJ / 2019 / Heart disease and stroke statistics-2019 update : a report from the American Heart Association / Circulation 139:e56~528
Organisation for Economic Cooperation and Development (OECD) / 2015 / Cardiovascular Disease and Diabetes: Policies for Better Health and Quality of Care / OECD Publishing
Lawlor DA / 2016 / Triangulation in aetiological epidemiology / Int J Epidemiol 45:1866~1886
Buttar HS / 2005 / Prevention of cardiovascular diseases : Role of exercise, dietary interventions, obesity and smoking cessation / Exp Clin Cardiol 10:229~249
Jee YH / 2018 / Cohort profile : the Korean Cancer Prevention Study-II(KCPS-II)Biobank / Int J Epidemiol 47:385~386f
Organisation for Economic Cooperation and Development (OECD) / 2015 / Cardiovascular Disease and Diabetes: Policies for Better Health and Quality of Care / OECD Publishing
Lawlor DA / 2016 / Triangulation in aetiological epidemiology / Int J Epidemiol 45:1866~1886
Buttar HS / 2005 / Prevention of cardiovascular diseases : Role of exercise, dietary interventions, obesity and smoking cessation / Exp Clin Cardiol 10:229~249
Jee YH / 2018 / Cohort profile : the Korean Cancer Prevention Study-II(KCPS-II)Biobank / Int J Epidemiol 47:385~386f
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