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논문 기본 정보

자료유형
학술저널
저자정보
Hyun Jin Oh (Seoul National University Bundang Hospital) So Yeon Hong (Seoul National University Bundang Hospital) Young Mi Jeong (Seoul National University Bundang Hospital) Kyung Suk Choi (Seoul National University Bundang Hospital) Eunsook Lee (Seoul National University Bundang Hospital) Euni Lee (Seoul National University) Yu Jung Kim (Seoul National University Bundang Hospital) Soo-Mee Bang (Seoul National University Bundang Hospital)
저널정보
대한혈액학회 Blood Research Blood Research Vol.55 No.3
발행연도
2020.1
수록면
151 - 158 (8page)

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BackgroundHematopoietic stem cell transplantation (HSCT) patients usually experience mucositis, musculoskeletal pain associated with high-dose chemotherapy, radiation, post-HSCT in-fection, or graft-versus-host disease. Pain management is important for the patients’ qual-ity of life. We evaluated appropriate opioid analgesic use in HSCT patients to propose effective pain management strategies.MethodsA retrospective analysis was conducted using electronic medical records of adult patients with HSCT treated with opioids for moderate to severe pain at Seoul National University Bundang Hospital. The numeric rating scale (NRS) was used in pain management. NRS scores of 4‒10 correspond to moderate to severe pain. Appropriate opioid analgesic use was evaluated following published cancer pain management guidelines.ResultsIn total, 119 cases were evaluated, including 369 episodes of moderate to severe pain. Mucositis-related, musculoskeletal, and headache pain occurred in 62.6%, 25.8%, and 6.0% of episodes, respectively. Frequently used opioids were intravenous tramadol (84.9%), fentanyl patch (73.9%), and intravenous morphine sulfate (68.9%). Intravenous and topical administrations were used for mucosal pain. In total, 95.0% of patients re-ceived appropriate short-acting opioids for initial pain management, 80.5% received ap-propriate doses of short-acting opioids, appropriate opioids dose adjustment was done after first assessment in 95.5% of patients, and 85.6% were converted to appropriate long-acting opioids.ConclusionShort-acting opioid analgesic use for initial pain management and dose adjustment after assessment were appropriate. However, initial and conversion dosages recommended by guidelines may be difficult to implement considering the severity of HSCT patients. Pain management guidelines specific for HSCT patients should be developed in the future.

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