지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Background: Oral mucositis during radiotherapy which is harmful to the patients with head and neck is suggested to be related to the oral hygiene and health. Therefore, we evaluated the oral health status in relation to the occurrence of mucositis among patients with head and neck cancer during radiotherapy. Methods: Tooth plaque index (PI), periodontal depth, and oral mucositis in 50 patients with head and neck cancer were examined by a dentist for 8 weeks after radiotherapy initiation. Cancer type and site were recorded based on the patients’ medical records. In addition, we assessed oral health-related quality of life. Results: The mean age of participants was 56.3 ± 11.6 years, with patients aged ＞ 60 years comprising the largest proportion of the mucositis group. The median (range) of the PI index were 0 (0-3) and 1 (0-3) among participants with mucositis and those without, respectively, with no significant difference (P = 0.761). The median (range) of the total Oral Health Impact Profile score were 54 (42-58) and 41 (14-70) among participants without mucositis and those with mucositis, respectively (P = 0.037). Conclusions: This study showed that patients who developed mucositis during radiotherapy had lower oral health-related quality of life than those who did not. However, there was no difference in oral health status according to mucositis. (J Cancer Prev 2019;24:43-47)
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Bowen JM / 2006 / Intestinal mucositis:the role of the Bcl-2 family, p53 and caspases in chemotherapy-induced damage / Support Care Cancer 14:713~731
Lockhart PB / 1981 / Alterations in the oral mucosa caused by chemotherapeutic agents. A histologic study / J Dermatol Surg Oncol 7:1019~1025
Sonis ST / 2000 / Defining mechanisms of action of interleukin-11 on the progression of radiation-induced oral mucositis in hamsters / Oral Oncol 36:373~381
Wang J / 2002 / Short-term inhibition of ADP-induced platelet aggregation by clopidogrel ameliorates radiation-induced toxicity in rat small intestine / Thromb Haemost 87:122~128
Sonis ST / 2004 / Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients / Cancer 100:1995~2025
Lockhart PB / 1981 / Alterations in the oral mucosa caused by chemotherapeutic agents. A histologic study / J Dermatol Surg Oncol 7:1019~1025
Sonis ST / 2000 / Defining mechanisms of action of interleukin-11 on the progression of radiation-induced oral mucositis in hamsters / Oral Oncol 36:373~381
Wang J / 2002 / Short-term inhibition of ADP-induced platelet aggregation by clopidogrel ameliorates radiation-induced toxicity in rat small intestine / Thromb Haemost 87:122~128
Sonis ST / 2004 / Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients / Cancer 100:1995~2025
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