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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 135 - 144 (10page)
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Nanocarrier-based biological fluorescent probes for ketamine and amphetamine have been prepared by conjugating red and green fluorescent nanoparticles (150-nm-sized) with anti-ketamine and anti-amphetamine antibodies, respectively, with the assistance of carbodiimide/N-hydroxysuccinimide. Biological fluorescent probes for ketamine and amphetamine could simultaneously detect these two drugs within a single fingermark by one-step test. Nanoparticles as carrier played dual-functional roles for not only fingermark visualization but also drug recognition. Latent fingermarks were visualized by the fluorescence signal generated from nanoparticles. The developed fingermarks clearly revealed ridge pattern and sufficient minutiae for individual identification. Ketamine and amphetamine were recognized by simply observing the colors of fluorescent images when the fingermark was checked in red and green channels. Detection limit of ketamine or amphetamine was 50 ng in fingermark. This work therefore provides a novel nanocarrier-based strategy of drug detection as well as personal identification with high selectivity, low background interference and fast testing, which can be further broadened to other drugs and molecules.
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참고문헌 (23)
참고문헌 신청
H. Faulds / 1880 / Nature 22:605
B. von Hofsten / 1954 / Nature 173:449
P. Hazarika / 2012 / Int. Ed 51:3524
Yin Zhong / 2017 / One-Step Synthesis of Nitrogen and Chlorine Co-Doped Carbon Quantum Dots for Detection of Fe3+ / NANO 12(11):65~73
Yongfeng Gao / 2018 / Ultrasensitive SERS-Based Immunoassay of Tumor Marker in Serum Using Au-Ag Alloy Nanoparticals and Ag/AgBr Hybrid Nanostructure / NANO 13(1):3~14
B. von Hofsten / 1954 / Nature 173:449
P. Hazarika / 2012 / Int. Ed 51:3524
Yin Zhong / 2017 / One-Step Synthesis of Nitrogen and Chlorine Co-Doped Carbon Quantum Dots for Detection of Fe3+ / NANO 12(11):65~73
Yongfeng Gao / 2018 / Ultrasensitive SERS-Based Immunoassay of Tumor Marker in Serum Using Au-Ag Alloy Nanoparticals and Ag/AgBr Hybrid Nanostructure / NANO 13(1):3~14
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