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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 164 - 171 (8page)
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Self-regulating temperature hyperthermia based on magnetic fluid with low Curie temperature is a moderately effective method for cancer treatment. The improvement of the properties of magnetic fluids is the key for application of this method. In this paper, Bi-doped LSMO magnetic nanoparticles were synthesized using a simple sol–gel method and coated by hyaluronic acid through high energy ball milling for their possible application in self-regulating temperature hyperthermia. The crystal structure, morphology, basic magnetic properties and heating properties of these nanoparticles in a high frequency magnetic field were investigated. It was found that the hyaluronic acid-coated La0.7Sr0.2Bi0.1MnO3 magnetic nanoparticles, with an average particle diameter of ~100 nm and a Curie temperature of 48 ℃, possess outstanding induction heating properties. The saturation heating temperature, specific absorption rate and effective specific absorption rate are 48 ℃, 117 W/g and 0.27 W/g · kHz · (kA/m2), respectively.
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