인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
Exfoliative dermatitis is an inflammatory disease which is accompanied by erythema and scaling on localized or generalized distribution caused by various etiologic factors. We present a case of 46-year-old woman with severe psoriasis who developed exfoliative dermatitis during treatment of biologics known as adalimumab and guselkumab. Five months after the treatment of adalimumab, she experienced the aggravation of psoriasis, and then developed exfoliative dermatitis. The authors changed her biologic agent from adalimumab to ustekinumab, ustekinumab to guselkumab because of unsatisfied therapeutic effect. After guselkumab treatment, exfoliative dermatitis developed again at 11 months of guselkumab treatment. Since then, she has been treated with guselkumab on schedule, and exfoliative dermatitis did not recur. Exfoliative dermatitis developed during biological treatment is known to be rare, and there have been no reported cases during the treatment of guselkumab, so we report it with a review of the literatures.
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