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자료유형
학술저널
저자정보
정경욱 (아주대학교 의과대학 소아청소년과학교실) 김지현 (삼성서울병원) 안강모 (삼성서울병원) 이소연 (한림대학교 성심병원 소아청소년과) 민택기 (순천향대학교) 편복양 (순천향대학교) 김윤희 (연세대학교) 김경원 (연세대학교) 손명현 (연세대학교) 김규언 (연세대학교) 장광천 (국민건강보험공단) 송태원 (인제대학교) 김정희 (인하대학교) 전유훈 (한림대학교 동탄성심병원 소아청소년과) 이용주 (한림대학교) 박용민 (건국대학교) 염혜영 (서울의료원 아토피센터) 김현희 (가톨릭대학교) 김우경 (인제대학교부속서울백병원) 이수영 (아주대학교)
저널정보
대한천식알레르기학회(구 대한알레르기학회) Allergy, Asthma & Immunology Research Allergy, Asthma & Immunology Research Vol.9 No.5
발행연도
2017.1
수록면
423 - 430 (8page)

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Purpose: Age-based causes and clinical characteristics of immediate-type food allergy (FA) have not been sufficiently studied. Therefore, we investigated age-dependent clinical profiles of FA in Korean children through an extensive multicenter investigation. Methods: Using a case report form developed by the authors, a retrospective medical record review was performed of patients (0-18 years old) diagnosed with immediate-type FA between September 2014 and August 2015 in 14 tertiary hospitals in Korea. Results: A total of 1,353 children and adolescents, 93% younger than 7 years, were enrolled in the present study, and 1,661 cases of immediate-type FA were recorded in these patients. The 7 major causative foods were cow’s milk (28.1%), hen’s eggs (27.6%), wheat (7.9%), walnuts (7.3%), peanuts (5.3%), buckwheat (1.9%), and shrimps (1.9%). Categorizing the patients into 4 age groups revealed that the most common causative food was different for each age group: cow’s milk (<2 years), walnuts (2-6 years), walnuts (7-12 years), and buckwheat (13-18 years). The onset time of symptoms was less than 10 minutes in 49%, between 10 and 30 minutes in 17%, and between 30 minutes and 2 hours in 34% of cases. Food-induced anaphylaxis was reported in 506 (30.5%) out of 1,661 cases, and the 7 major causes of food-induced anaphylaxis was cow’s milk (27.5%), hen’s eggs (21.9%), wheat (11.3%), walnuts (10.5%), peanuts (5.9%), buckwheat (4.2%), and pine nuts (3.0%). The proportion of anaphylaxis was highest in the patients allergic to buckwheat (67.7%), followed by those allergic to pine nuts (57.7%), walnuts (43.8%), wheat (43.5%), and peanuts (34.1%). Conclusions: The 5 major causative foods of immediate-type FA in Korean children were cow’s milk, hen’s eggs, wheat, walnuts, and peanuts. The distribution of causative foods was considerably distinctive according to different age groups. Anaphylaxis was reported in 30.5% of immediate-type FA cases.

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