지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 288 - 296 (9page)
이용수
초록· 키워드
오류제보하기
Objective. To investigate the associations among platelet indices, disease activity scores, and inflammatory markers in axial spondyloarthritis, and to determine the relation between platelet indices and inflammation measured on magnetic resonance imaging (MRI). Methods. The study included 161 patients who fulfilled Assessment of Spondyloarthritis International Society criteria. Platelet indices such as mean platelet volume (MPV), plateletcrit (PCT), platelet large cell ratio (PLCR), and platelet distribution width (PDW) were measured. Ninety patients underwent sacroiliac (SI) MRI at baseline. Bone marrow edema (BME) and erosion on MRI were scored using the SPondyloArthritis Research Consortium of Canada (SPARCC) method. Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Ankylosing Spondylitis Disease Activity Score (ASDAS) and spinal radiologic progression were also assessed. The associations among platelet indices and disease activity scores and inflammatory markers were evaluated. Results. Of the 161 patients, 130 (81%) were male. MPV, PLCR, and PDW were negatively associated with ASDAS and inflammatory marker expression, whereas PCT was positively associated with these parameters. MPV, PLCR, and PDW were negatively associated with BME and erosion scores on SI MRI. However, platelet indices were not associated with the BASDAI and BASFI. The mean erythrocyte sedimentation rate, C-reactive protein, and BME and erosion scores were significantly higher in patients with low MPV. Changes in MPV, PCT, and PDW at baseline and after one year were associated with changes in ASDAS and inflammatory marker expression. Conclusion. Platelet indices are associated with ASDAS, inflammatory marker levels, and severity of BME and erosion measured on MRI. (J Rheum Dis 2016;23:288-296)
목차
등록된 정보가 없습니다.
참고문헌 (40)
참고문헌 신청
Dougados M / 2011 / Spondyloarthritis / Lancet 377:2127~2137
Rudwaleit M / 2009 / The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal / Ann Rheum Dis 68:770~776
Garrett S / 1994 / A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index / J Rheumatol 21:2286~2291
van der Heijde D / 2009 / ASDAS, a highly discriminatory ASAS-endorsed disease activity score in patients with ankylosing spondylitis / Ann Rheum Dis 68:1811~1818
Reveille JD / 2015 / Biomarkers for diagnosis, monitoring of progression, and treatment responses in ankylosing spondylitis and axial spondyloarthritis / Clin Rheumatol 34:1009~1018
Rudwaleit M / 2009 / The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal / Ann Rheum Dis 68:770~776
Garrett S / 1994 / A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index / J Rheumatol 21:2286~2291
van der Heijde D / 2009 / ASDAS, a highly discriminatory ASAS-endorsed disease activity score in patients with ankylosing spondylitis / Ann Rheum Dis 68:1811~1818
Reveille JD / 2015 / Biomarkers for diagnosis, monitoring of progression, and treatment responses in ankylosing spondylitis and axial spondyloarthritis / Clin Rheumatol 34:1009~1018
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Platelet Distribution Width and Mean Platelet Volume Are Not Correlated with the Disease Activity Indices of Ankylosing Spondylitis
대한류마티스학회지
2017 .01
-
Association Between High Platelet Indices and Proteinuria in Patients With Hypertension
Annals of Laboratory Medicine
2015 .01
-
Evaluation of Platelet Indices in Lung Cancer Patients
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Comparison of the Prognostic Value of Platelet-Related Indices in Biliary Tract Cancer Undergoing Surgical Resection
Cancer Research and Treatment
2021 .01
-
Mean Platelet Volume Is Elevated in Patients with Psoriasis Vulgaris
Yonsei Medical Journal
2015 .01
-
Relations of Platelet Indices with Endometrial Hyperplasia and Endometrial Cancer
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
High Mean Platelet Volume Is Associated with Cerebral White Matter Hyperintensities in Non-Stroke Individuals
Yonsei Medical Journal
2023 .01
-
Count of platelet and mean platelet volume score: serologic prognostic factor in patients with oral squamous cell carcinoma
대한구강악안면외과학회지
2017 .01
-
Platelet Indices May be Useful in Discrimination of Benign and Malign Endometrial Lesions, and Early and Advanced Stage Endometrial Cancer
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
The Fibrinogen to Mean Platelet Volume Ratio Can Predict Overall Survival of Patients with Non-Metastatic Gastric Cancer
Journal of Gastric Cancer
2018 .12
-
Comparison of mean platelet volume levels in coronary artery ectasia and healthy people: systematic review and meta-analysis
Blood Research
2018 .01
-
Is increased Mean platelet volume associated with neurologic outcome after non-traumatic subarachnoid hemorrhage?
대한응급의학회지
2023 .04
-
Hemoglobin A1c, Not Glycated Albumin, Can Independently Reflect the Ankylosing Spondylitis Disease Activity Score
대한류마티스학회지
2018 .01
-
Lack of Variation in Inflammatory Hematological Parameters between Benign Nodular Goiter and Papillary Thyroid Cancer
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
양성돌발성두위현훈에서 혈소판 지표의 역할에 대한 연구
Research in Vestibular Science
2021 .12
-
Can Head and Neck Cancers Be Detected with Mean Platelet Volume?
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Are Platelet Indices of Clinical Use to Monitor Disease Activity and Inflammatory Burden in Axial Spondyloarthritis?
대한류마티스학회지
2016 .01
-
Mean Platelet Volume as an Independent Predictive Marker for Pathologic Complete Response after Neoadjuvant Chemotherapy in Patients with Locally Advanced Breast Cancer
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Quantifying Bone Marrow Edema Adjacent to the Lumbar Vertebral Endplate on Magnetic Resonance Imaging: A Cross-Sectional Study of Patients with Degenerative Lumbar Disease
Asian Spine Journal
2022 .04
-
Diagnostic Power of Blood Parameters as Screening Markers in Gastric Cancer Patients
Asian Pacific journal of cancer prevention : APJCP
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0