지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objective. To analyze radiologic findings of cervical involvement in ankylosing spondylitis (AS) patients, determine its association with structural severity and clinical variables, and to divide radiologic findings of atlantoaxial ankylosis (AAA) in AS patients into three anatomical components. Methods. The study includes 150 AS patients with either AAA (62 patients) or atlantoaxial subluxation (AAS, 88 patients) who underwent plain radiography of the cervical spine on flexion at our tertiary center for rheumatic diseases. The study subjects’ medical records were reviewed. Lateral plain radiographs of the cervical spine were analyzed by a musculoskeletal radiologist. We compared the results of the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) between AAS and AAA patients to determine if mSASSS was related to severity or duration of AS. Results. The mean duration of illness in AS patients with AAA was 19.3 years, and in AAS patients 13.7 years (p＜0.01). The mean total mSASSS of AS patients with AAA was 40.1, and of AAS patients 16.5 (p＜0.001), and was positively associated with the development of AAA and AAS. The odds ratio (OR) of AAA development by cervical spine mSASSS change was higher (OR, 1.079) than the OR (1.049) of lumbar spine mSASSS even after adjusting for age, sex, and disease duration. Conclusion. Although AAA is described infrequently, we found from our data that it is another manifestation of cervical spine involvement in longstanding AS and is related to severity of AS reflected by higher cervical mSASSS.
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참고문헌 (16)
참고문헌 신청
Gouveia EB / 2012 / Ankylosing spondylitis and uveitis : overview / Rev Bras Reumatol 52:742~756
Archer JR / 1999 / Ankylosing spondylitis : time to focus on ankylosis / J Rheumatol 26:761~764
Martel W / 1961 / The occipito-atlanto-axial joints in rheumatoid arthritis and ankylosing spondylitis / Am J Roentgenol Radium Ther Nucl Med 86:223~240
Hunter T / 1989 / The spinal complications of ankylosing spondylitis / Semin Arthritis Rheum 19:172~182
Liang CL / 2002 / Dissociation of atlantoaxial junction in ankylosing spondylitis : case report / J Trauma 53:1173~1175
Archer JR / 1999 / Ankylosing spondylitis : time to focus on ankylosis / J Rheumatol 26:761~764
Martel W / 1961 / The occipito-atlanto-axial joints in rheumatoid arthritis and ankylosing spondylitis / Am J Roentgenol Radium Ther Nucl Med 86:223~240
Hunter T / 1989 / The spinal complications of ankylosing spondylitis / Semin Arthritis Rheum 19:172~182
Liang CL / 2002 / Dissociation of atlantoaxial junction in ankylosing spondylitis : case report / J Trauma 53:1173~1175
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