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자료유형
학술저널
저자정보
류재현 (중앙보훈병원) 김윤범 (중앙보훈병원) 정태영 (중앙보훈병원) 김선일 (아주대학교) 변석수 (서울대학교) 권동덕 (전남대학교) 김덕윤 (대구가톨릭대학교) 오태희 (성균관대학교) 유탁근 (을지대학교) 고우진 (연세대학교)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.31 No.6
발행연도
2016.1
수록면
957 - 962 (6page)

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Prostate cancer is the most common type of male cancer worldwide. Although radical prostatectomy (RP) is advised for prostate cancer in patients with a life expectancy of more than 10 years by various guidelines, most elderly men still do not undergo the procedure regardless of increasing life expectancy. This study aimed to determine whether RP is suitable for patients with prostate cancer aged 75 years or older. A retrospective study of patients who underwent RP at 6 institutions between 2005 and 2012 was conducted. Patients were divided into 2 groups at the time of surgery: 65-69 years (younger group) and 75 years or older (older group). We compared clinical characteristics, pathological results, complication rates, and recurrence-free survival between the two groups. Compared with the younger group, the older group had significantly higher preoperative serum prostate-specific antigen level, pre- and postoperative Eastern Cooperative Oncology Group (ECOG) performance status grade, hypertension prevalence, and Gleason score at biopsy and RP. However, except urinary incontinence, there were no statistically significant differences in the peri- and post-operative complications. After median follow-up periods of 36 months (younger group) and 40 months (older group), the biochemical recurrencefree survival rates were not significantly different (P = 0.581). Although the urinary incontinence rate was higher in the older group, RP was a suitable option for selected Korean men aged 75 years or older with limited complication rates and excellent outcomes similar to those for patients aged 65-69 years.

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