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학술저널
저자정보
김헌성 (가톨릭대학교) 김현아 (숙명여자대학교) 정유진 (가톨릭대학교) 김동민 (가톨릭대학교) 양소정 (가톨릭대학교(성의교정)) 백선정 (가톨릭대학교) 이승환 (가톨릭대학교) 조재형 (가톨릭대학교) 최인영 (가톨릭대학교) 윤건호 (가톨릭대학교)
저널정보
대한내분비학회 Endocrinology and Metabolism Endocrinology and Metabolism Vol.32 No.1
발행연도
2017.1
수록면
90 - 98 (9page)

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Background: The increasing use of electronic medical record (EMR) systems for documenting clinical medical data has led to EMRdata being increasingly accessed for clinical trials. In this study, a database of patients who were prescribed statins for the first timewas developed using EMR data. A clinical data mart (CDM) was developed for cohort study researchers. Methods: Seoul St. Mary’s Hospital implemented a clinical data warehouse (CDW) of data for ~2.8 million patients, 47 million prescriptionevents, and laboratory results for 150 million cases. We developed a research database from a subset of the data on the basisof a study protocol. Data for patients who were prescribed a statin for the first time (between the period from January 1, 2009 to December31, 2015), including personal data, laboratory data, diagnoses, and medications, were extracted. Results: We extracted initial clinical data of statin from a CDW that was established to support clinical studies; the data was refinedthrough a data quality management process. Data for 21,368 patients who were prescribed statins for the first time were extracted. We extracted data every 3 months for a period of 1 year. A total of 17 different statins were extracted. It was found that statins werefirst prescribed by the endocrinology department in most cases (69%, 14,865/21,368). Conclusion: Study researchers can use our CDM for statins. Our EMR data for statins is useful for investigating the effectiveness oftreatments and exploring new information on statins. Using EMR is advantageous for compiling an adequate study cohort in a shortperiod.

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