지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.70 No.3
- 발행연도
- 2017.1
- 수록면
- 305 - 310 (6page)
이용수
초록· 키워드
오류제보하기
Background: To establish the prognostic value of procalcitonin, C-reactive protein and cholesterol levels for mortality in patients with an infection and multiple organ dysfunction. Methods: A prospective case-control study was performed, including 67 patients admitted to the intensive care unit with an infection and multiple organ dysfunction in whom cholesterol, procalcitonin, and C-reactive protein levels were measured on admission and during the course of treatment. Results: The associations between in-hospital mortality and procalcitonin, C-reactive protein, and cholesterol levels were analyzed. Logistic regression analysis showed that cholesterol (odds ratio [OR], 1.858; 95% CI, 1.170–2.949; P = 0.009) and C-reactive protein (OR, 4.408; 95% CI, 2.019–9.624; P < 0.001) levels were predictors of mortality. A receiver operating characteristic curve analysis yielded an area under the curve (AUC) of 0.774 and 95% CI of 0.693–0.855 (P < 0.001) for C-reactive protein, an AUC of 0.66 and 95% CI of 0.535–0.784 (P = 0.019) for procalcitonin, and an AUC of 0.654 and 95% CI of 0.593–0.715 (P < 0.001) for cholesterol as predictors of mortality. When combined with the bioscore system for mortality, these markers yielded an AUC of 0.845 and 95% CI of 0.770–0.921 (P < 0.001), with sensitivity of 89.1% and specificity of 83.1%. Conclusions: The combination of procalcitonin, C-reactive protein, and cholesterol levels in a single scoring system yielded high predictive value for mortality.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Singer M / 2016 / The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) / JAMA 315:801~810
Mancini N / 2015 / Microbiological diagnosis of sepsis: the confounding effects of a 'gold standard' / Methods Mol Biol 1237:1~4
Andrade SS / 2008 / Advances in the microbiological diagnosis of sepsis / Shock 30(Suppl 1):41~46
Luo XP / 2009 / Comparison of three different organ failure assessment score systems in predicting outcome of severe sepsis / Zhonghua Wai Ke Za Zhi 47:48~50
Liu B / 2013 / Diagnostic value and prognostic evaluation of Presepsin for sepsis in an emergency department / Crit Care 17:R244
Mancini N / 2015 / Microbiological diagnosis of sepsis: the confounding effects of a 'gold standard' / Methods Mol Biol 1237:1~4
Andrade SS / 2008 / Advances in the microbiological diagnosis of sepsis / Shock 30(Suppl 1):41~46
Luo XP / 2009 / Comparison of three different organ failure assessment score systems in predicting outcome of severe sepsis / Zhonghua Wai Ke Za Zhi 47:48~50
Liu B / 2013 / Diagnostic value and prognostic evaluation of Presepsin for sepsis in an emergency department / Crit Care 17:R244
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