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김남수; 이재현; 김달식; 이혜수; 최삼임; 조용곤

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자료유형: 학술저널

저자정보: 김남수 (전북대학교 의학전문대학원 진단검사의학교실) 이재현 (전북대학교 의학전문대학원 진단검사의학교실 전북대학교 임상의학연구소-전북대학교병원 의생명) 김달식 (전북대학교 의학전문대학원 진단검사의학교실 전북대학교 임상의학연구소-전북대학교병원 의생명) 이혜수 (전북대학교 의학전문대학원 진단검사의학교실 전북대학교 임상의학연구소-전북대학교병원 의생명) 최삼임 (전북대학교 의학전문대학원 진단검사의학교실 전북대학교 임상의학연구소-전북대학교병원 의생명) 조용곤 (전북대학교 의학전문대학원 진단검사의학교실 전북대학교 임상의학연구소-전북대학교병원 의생명)

저널정보: 대한수혈학회 대한수혈학회지 대한수혈학회지 제29권 제1호

발행연도: 2018.1

수록면: 79 - 85 (7page)

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An ABO-incompatible transfusion is a very rare event but it can cause severe adverse effects, including death. The prognosis is affected by various factors, such as the volume of infusion, underlying diseases, and immunologic state. Until now, however, there has been no consensus regarding the treatment of an ABO-incompatible transfusion except for conservative treatment. A 57 year-old male patient visited the authors’ emergency unit with multiple trauma due to a car accident. He had a deep laceration on his left neck accompanied by severe bleeding. Because of his low blood pressure and low hemoglobin level due to bleeding, an emergency transfusion was attempted. Unfortunately, one unit of RBC was transfused incorrectly into the patient due to a clerical error during the identification of the patient. The patient was typed as O, RhD positive; the RBC administered was A, RhD positive. After the transfusion, the patient showed an acute hemolytic transfusion reaction due to gross hematuria. Plasma exchange was attempted and medical treatment with high dose steroid with diuretics was done simultaneously. Two cycles of plasma exchange were done and the patient appeared to recover from the acute adverse effects of the transfusion. The plasma exchange was stopped and medical treatments for the transfusion reactions were maintained for ten days. The patient recovered fully and was discharged after one month. Based on this case, although more studies are necessary for approval as a standard therapy, this case suggests that immediate plasma exchange with medical treatment can be very helpful for eliminating the isoagglutinins in ABO-incompatible transfusions.

참고문헌 (12)

참고문헌 신청

Linden JV / 2000 / Transfusion errors in New York State: an analysis of 10 years' experience / Transfusion 40:1207~1213

Janatpour KA / 2008 / Clinical outcomes of ABO-incompatible RBC transfusions / Am J Clin Pathol 129:276~281

Sazama K / 1990 / Reports of 355 transfusionassociated deaths: 1976 through 1985 / Transfusion 30:583~590

Fung MK / 2014 / Technical manual / American Association of Blood Banks :673~674

Han KS / 2014 / Transfusion medicine / Korea Medical Book Publisher :292~293

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김남수

소속기관 전북대학교 의학전문대학원 진단검사의학교실

주요연구분야 의약학 > 임상의학 > 임상병리학

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