Cerebrospinal Fluid Leakage after Surgeries on the Thoracic Spine: A Review of 362 Cases

Panpan Hu; Miao Yu; Xiaoguang Liu; Zhongjun Liu; Liang Jiang Feng Wei; Zhongqiang Chen

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자료유형: 학술저널

저자정보: Panpan Hu (Peking University Third Hospital) Miao Yu (Peking University Third Hospital) Xiaoguang Liu (Peking University Third Hospital) Zhongjun Liu (Peking University Third Hospital) Liang Jiang Feng Wei (Peking University Third Hospital) Zhongqiang Chen (Peking University Third Hospital)

저널정보: 대한척추외과학회 Asian Spine Journal Asian Spine Journal Vol.10 No.3

발행연도: 2016.1

수록면: 472 - 479 (8page)

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Study Design: A retrospective clinical review. Purpose: To describe the incidence of cerebrospinal fluid leakage (CSFL) after thoracic decompression and examine the CSFL predisposing clinical factors. Overview of Literature: CSFL is a common complication following thoracic decompression but has not been sufficiently addressed in former studies. Methods: A cohort of 362 cases of thoracic decompression from February of 2005 to June of 2013 was examined. The case medical records were reviewed and the occurrence of CSFL and the related clinical parameters were noted. The incidence of CSFL for the entire cohort and each surgical approach were described. Besides, the relationship between CSFL and other clinical parameters were assessed, of which odds ratio values of all CSFL-associated parameters were calculated using multivariate logistic regression analysis. Results: The incidence of CSFL for the entire cohort was 32.3%. Different surgical approaches had different incidences of CSFL, and circumferential decompression had the highest incidence. Though many different clinical parameters were related to the occurrences of CSFL, being older than 52 years, having ossification of the posterior longitudinal ligament or having longer operative segments than 3 vertebrae were significant risk factors for CSFL (p <0.05). Besides, surgeries on the mid-thoracic spine had an increased risk of CSFL (p <0.05). Conclusions: From our analysis, CSFL was a common complication after thoracic decompression with the incidence of up to 32.3%. This study identified the predisposing clinical factors, and spinal surgeons should be aware of these risk factors to reduce its incidence.

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