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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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There have been recent advances in the hyperacute treatment and secondary prevention of ischemic stroke. Thrombolysis with intravenous tissue plasminogen activator has been approved for a 3 to 4.5 hour time window, but the recent controversy over the optimal dose has not been resolved. Five endovascular trials published in 2015 have shown dramatically positive results. Regarding secondary prevention of ischemic stroke, a study suggesting the beneficial effect of a short course of dual antiplatelet therapy has been published. Non-vitamin K antagonist oral anticoagulation agents have been approved for stroke prevention in non-valvular atrial fibrillation. Here, we review these recent advances in ischemic stroke management.
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참고문헌 (24)
참고문헌 신청
1995 / Tissue plasminogen activator for acute ischemic stroke: the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group / N Engl J Med 333:1581~1587
Wahlgren N / 2007 / Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study / Lancet 369:275~282
Rha JH / 2014 / Thrombo-lysis for acute ischaemic stroke with alteplase in an Asian population: results of the multicenter, multinational Safe Imple-mentation of Thrombolysis in Stroke-Non-European Union World (SITS-NEW) / Int J Stroke 9(A100):93~101
Hacke W / 1998 / Randomised double-blind placebo-controlled trial of thrombolytic therapy with intra-venous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators / Lancet 352:1245~1251
Albers GW / 2002 / ATLANTIS trial results for patients treated within 3 hours of stroke onset / Stroke 33:493~496
Wahlgren N / 2007 / Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study / Lancet 369:275~282
Rha JH / 2014 / Thrombo-lysis for acute ischaemic stroke with alteplase in an Asian population: results of the multicenter, multinational Safe Imple-mentation of Thrombolysis in Stroke-Non-European Union World (SITS-NEW) / Int J Stroke 9(A100):93~101
Hacke W / 1998 / Randomised double-blind placebo-controlled trial of thrombolytic therapy with intra-venous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators / Lancet 352:1245~1251
Albers GW / 2002 / ATLANTIS trial results for patients treated within 3 hours of stroke onset / Stroke 33:493~496
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