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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 19 - 29 (11page)
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Objectives: Breast conserving surgery (BCS) for early breast cancer is now an accepted treatment, but there are controversies about its comparability with mastectomy. Thus, we investigated the survival outcomes who underwent BCS and modified radical mastectomy (MRM). Methods: In this retrospective review, we analyzed the survival outcomes of 618 patients with early breast cancer who underwent two different surgery from January 2002 to December 2009. Postoperative pathologic difference, disease free survival period, overall survival period, recurrence pattern, recurrent rate and site were compared. In addition, preoperative patients data are also collected. Results: Disease free survival period of MRM and BCS was 108.46 months and 80.82 months, respectively (P < 0.01). However, there was no significant correlation between overall survival period and operative methods (P = 0.67). In addition, recurrence pattern (P = 0.21), recurrent rate (P = 0.36) and site (P = 0.45, P = 0.09) were not associated with operative method. Conclusions: In this study, we can suggest that early breast cancer patients could improve their disease free survival if they underwent MRM. So, when we operate high risk breast cancer patients, MRM could be considered for their disease free life. Further studies may be required to establish appropriate strategy of surgery for early breast cancer.
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등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Lee JS / 2004 / Clinical Analysis of breast cancer patients treated with surgery / J Korean Breast Cancer Soc 7:174~179
Natarajan L / 2009 / Time-varying effects of prognostic factors associated with disease-free survival in breast cancer / Am J Epidemiol 169:1463~1470
Lee JB / 2001 / Factors influencing the recurrence of breast cancer following modified radical mastectomy / J Korean Breast Cancer Soc 4:128~135
van Dongen JA / 2000 / Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 Trial / J Natl Cancer Inst 92:1143~1150
McCready D / 2005 / Surgical management of early stage invasive breast cancer: a practice guideline / Can J Surg 48:185~194
Natarajan L / 2009 / Time-varying effects of prognostic factors associated with disease-free survival in breast cancer / Am J Epidemiol 169:1463~1470
Lee JB / 2001 / Factors influencing the recurrence of breast cancer following modified radical mastectomy / J Korean Breast Cancer Soc 4:128~135
van Dongen JA / 2000 / Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 Trial / J Natl Cancer Inst 92:1143~1150
McCready D / 2005 / Surgical management of early stage invasive breast cancer: a practice guideline / Can J Surg 48:185~194
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