지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 13 - 18 (6page)
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초록· 키워드
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Purpose: Creatine kinase (CK) elevation is caused by rhabdomyolysis, intense exercise, muscle damage, and several drugs. This study evaluated the clinical significance of elevated serum CK levels in patients with an intensive care unit (ICU) and their effects on muscle strength. Methods: The database of 179 patients, who were examined with CK a t least once among patients in the Samsung Medical Center ICU database, was reviewed retrospectively. Fortyeight patients with a myocardial infarction were excluded and 131 patients were analyzed. The clinical features of patients with an elevated CK of more than 2,000 IU/L (more than 10 times the normal value) and those who did not were compared. Results: The ICU stay days were longer in the high elevation group than the other group (8.6 days vs. 21.7 days, p=0.002). The high elevation group was more likely to go to other treatment centers than home after discharge (14.6% vs. 60.0%, p=0.007). When the Medical Research Council scale was measured, the score of the high elevation group was lower than that of the other group (17.2 vs. 13.3, p=0.006). Conclusion: Patients with high CK levels were more likely to receive invasive treatment in the ICU, so their muscle strength may decrease with increasing ICU stay and were less likely to be discharged home because of difficulties in living alone. Therefore, in patients with high CK, anticipating long-term treatment in an ICU, minimizing muscle loss, and maintaining functional muscle strength through active rehabilitation will be helpful for the prognosis of the patient. (J Acute Care Surg 2018;8:13-18)
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참고문헌 (29)
참고문헌 신청
Rosalki SB / 1998 / Low serum creatine kinase activity / Clin Chem 44:905
Morandi L / 2006 / High plasma creatine kinase: review of the literature and proposal for a diagnostic algorithm / Neurol Sci 27:303~311
Brown CV / 2004 / Preventing renal failure in patients with rhabdomyolysis: do bicarbonate and mannitol make a difference? / J Trauma 56:1191~1196
Vanholder R / 2000 / Rhabdomyolysis / J Am Soc Nephrol 11:1553~1561
Bosch X / 2009 / Rhabdomyolysis and acute kidney injury / N Engl J Med 361:62~72
Morandi L / 2006 / High plasma creatine kinase: review of the literature and proposal for a diagnostic algorithm / Neurol Sci 27:303~311
Brown CV / 2004 / Preventing renal failure in patients with rhabdomyolysis: do bicarbonate and mannitol make a difference? / J Trauma 56:1191~1196
Vanholder R / 2000 / Rhabdomyolysis / J Am Soc Nephrol 11:1553~1561
Bosch X / 2009 / Rhabdomyolysis and acute kidney injury / N Engl J Med 361:62~72
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