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논문 기본 정보

자료유형
학술저널
저자정보
Jin Hae Lee (Department of Ophthalmology Nune Eye Hospital) Jiwon Baek (Department of Ophthalmology The Catholic University of Korea Seoul St. Mary’s Hospital) Won Ki Lee (Department of Ophthalmology The Catholic University of Korea Seoul St. Mary’s Hospital)
저널정보
한국망막학회 Journal of Retina Journal of Retina Vol.2 No.1
발행연도
2017.1
수록면
45 - 50 (6page)

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Purpose: To report an ocular relapse of diffuse large B cell uterine lymphoma. Case summary: A 51-year-old woman with diffuse large B cell uterine lymphoma reached and maintained complete remission for four consecutive years at six re-staging evaluations after six cycles of cyclophosphamide, hydroxyl-daunorubicin, oncovin, and prednisone chemotherapy. Late ocular relapse of diffuse large B cell lymphoma may simply present as cells in the vitreous cavity without any systemic involvement. Diagnostic vitrectomy was performed, and the cytopathologic exam showed monoclonal B cell origin lymphoma. The patient was given a repeat course of intravitreal methotrexate injections and six cycles of high-dose methotrexate and Ara-C intravenously. Despite the chemotherapy, brain involvement was detected 26 months after the diagnosis. However, the patient remains alive after 48 months. Conclusions: In selected patients with intraocular lymphoma, having a high degree of clinical suspicion is the most important factor required to make the diagnosis; diagnostic vitrectomy is useful for both diagnostic and therapeutic purposes.

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