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자료유형
학술저널
저자정보
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.30 No.3
발행연도
2015.1
수록면
296 - 300 (5page)

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Serum anti-Müllerian hormone (AMH) levels are regarded as an age-specific marker forpredicting the ovarian reserve in women of reproductive age. Some studies have shownthat the luteinizing hormone (LH)/follicle stimulating hormone (FSH) ratio can be used as apredictor of ovarian reserve. The purpose of this study was to assess the variation of LH/FSH ratio with aging and to evaluate the correlation between serum LH/FSH ratio and AMHlevels as a predictor of the ovarian reserve in normo-ovulatory women. We retrospectivelyanalyzed the day 3 serum hormone levels in 1,251 patients (age range: 20-50 yr) betweenJanuary 2010 and January 2011. We divided the patients into 6 groups according to theirage. Relation between serum AMH level and LH/FSH ratio was analyzed statistically. Theserum AMH level was inversely correlated with age (r = -0.400, P < 0.001). A significantnegative correlation was found between serum LH/FSH ratio and age (r = -0.213,P < 0.001). There was a significant partial correlation between serum LH/FSH ratio andAMH level when adjusted by age (r = 0.348, P < 0.001). The LH/FSH ratio could beconsidered as a useful marker for the ovarian reserve and could be applied to the clinicalevaluation with AMH.

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