The Clinical Features and Predictive Risk Factors for Reoperation in Patients With Perianal Crohn Diseases; A Multi-Center Study of a Korean Inflammatory Bowel Disease Study Group

이재범; 윤서구; 박규주; 이강영; 김대동; 윤상남; 유창식; IBD연구회

추천

검색

자료유형: 학술저널

저자정보: 이재범 (대항병원) 윤서구 (서울송도병원) 박규주 (서울대학교) 이강영 (연세대학교) 김대동 (대구가톨릭대학교) 윤상남 (한림대학교) 유창식 (울산대학교) IBD연구회 (대한대장항문학회)

저널정보: 대한대장항문학회 Annals of Coloproctology Annals of Coloproctolgy Vol.31 No.5

발행연도: 2015.1

수록면: 176 - 181 (6page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Purpose: Perianal lesions are common in Crohn disease, but their clinical course is unpredictable. Nevertheless, predicting the clinical course after surgery for perianal Crohn disease (PCD) is important because repeated operations may decrease patient’s quality of life. The aim of this study was to predict the risk of reoperation in patients with PCD. Methods: From September 1994 to February 2010, 377 patients with PCD were recruited in twelve major tertiary university-affiliated hospitals and two specialized colorectal hospitals in Korea. Data on the patient’s demographics, clinical features, and surgical outcomes were analyzed. Results: Among 377 patients, 227 patients were ultimately included in the study. Among the 227 patients, 64 patients underwent at least one reoperation. The median period of reoperation following the first perianal surgery was 94 months. Overall 3-year, 5-year, and 10-year cumulative rates of reoperation-free individuals were 68.8%, 61.2%, and 50.5%, respectively. In multivariate analysis (Cox-regression hazard model), reoperation was significantly correlated with an age of onset less than 20 years (hazard ratio [HR], 1.93; 95% confidence interval [CI], 1.07–3.48; P = 0.03), history of abdominal surgery (HR, 1.99; 95% CI, 1.08–3.64; P = 0.03), and the type of surgery. Among types of surgery, fistulotomy or fistulectomy was associated with a decreased incidence of reoperation in comparison with incision and drainage (HR, 0.19; 95% CI, 0.09–0.42; P < 0.001). Conclusion: Young age of onset and a history of abdominal surgery were associated with a high risk of reoperation for PCD, and the risk of reoperation were relatively low in fistulotomy or fistulectomy procedures.

참고문헌 (25)

참고문헌 신청

Shin DH / 2011 / Increasing incidence of inflammatory bowel disease among young men in Korea between 2003 and 2008 / Dig Dis Sci 56:1154~1159

Yang SK / 2008 / Epidemiology of inflammatory bowel disease in the Songpa-Kangdong district, Seoul, Korea, 1986-2005: a KASID study / Inflamm Bowel Dis 14:542~549

Harper PH / 1987 / The long-term outcome in Crohn’s disease / Dis Colon Rectum 30:174~179

Schwartz DA / 2002 / The natural history of fistulizing Crohn’s disease in Olmsted County, Minnesota / Gastroenterology 122:875~880

Hellers G / 1980 / Occurrence and outcome after primary treatment of anal fistulae in Crohn’s disease / Gut 21:525~527

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!