지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 248 - 253 (6page)
이용수
초록· 키워드
오류제보하기
Purpose: Anogential distance (AGD) and the 2:4 digit length ratio appear to provide a reliable guide to fetal androgen exposure. We intended to investigate the current status of penile size and the relationship between penile length and AGD or digit length according to birth weight in Korean newborn infants.
Materials and Methods: Between May 2013 and February 2014, among a total of 78 newborn male infants, 55 infants were prospectively included in this study. Newborn male infants with a gestational age of 38 to 42 weeks and birth weight>2.5 kg were assigned to the NW group (n=24) and those with a gestational age<38 weeks and birth weight<2.5 kg were assigned to the LW group (n=31). Penile size and other variables were compared between the two groups.
Results: Stretched penile length of the NW group was 3.3±0.2 cm, which did not differ significantly from that reported in 1987. All parameters including height, weight, penile length, testicular size, AGD, and digit length were significantly lower in the LW group than in the NW group. However, there were no significant differences in AGD ratio or 2:4 digit length ratio between the two groups.
Conclusions: The penile length of newborn infants has not changed over the last quarter century in Korea. With normal penile appearance, the AGD ratio and 2:4 digit length ratio are consistent irrespective of birth weight, whereas AGD, digit length, and penile length are significantly smaller in newborns with low birth weight.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Welsh M / 2008 / Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism / J Clin Invest 118:1479~1490
Macleod DJ / 2010 / Androgen action in the masculinization programming window and development of male reproductive organs / Int J Androl 33:279~287
van den Driesche S / 2011 / Relative importance of prenatal and postnatal androgen action in determining growth of the penis and anogenital distance in the rat before, during and after puberty / Int J Androl 34(6 Pt 2):e578~e586
Drake AJ / 2009 / Glucocorticoids amplify dibutyl phthalateinduced disruption of testosterone production and male reproductive development / Endocrinology 150:5055~5064
Kim KS / 2002 / Expression of the androgen receptor and 5 alpha-reductase type 2 in the developing human fetal penis and urethra / Cell Tissue Res 307:145~153
Macleod DJ / 2010 / Androgen action in the masculinization programming window and development of male reproductive organs / Int J Androl 33:279~287
van den Driesche S / 2011 / Relative importance of prenatal and postnatal androgen action in determining growth of the penis and anogenital distance in the rat before, during and after puberty / Int J Androl 34(6 Pt 2):e578~e586
Drake AJ / 2009 / Glucocorticoids amplify dibutyl phthalateinduced disruption of testosterone production and male reproductive development / Endocrinology 150:5055~5064
Kim KS / 2002 / Expression of the androgen receptor and 5 alpha-reductase type 2 in the developing human fetal penis and urethra / Cell Tissue Res 307:145~153
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