메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
양승훈 (연세대학교) 정재흥 (연세대학교) 엄민섭 (연세대학교) 송재만 (연세대학교) 정현철 (연세대학교) 채윤병 (충북대학교) 이창민 (연세대학교) 김광진 (연세대학교)
저널정보
대한비뇨기과학회 Investigative and Clinical Urology Investigative and Clinical Urology Vol.56 No.7
발행연도
2015.1
수록면
515 - 518 (4page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Purpose: It is well known that testicular germ cell tumors arise with increased frequency in patients with cryptorchidism. In addition,intratubular germ cell neoplasia (ITGCN) is a precursor lesion to testicular germ cell tumor. Approximately 50% of patientswith ITGCN will develop an invasive of testicular germ cell tumors within 5 years. Therefore, we evaluated that the incidence ofITGCN in postpubertal cryptorchidism. Materials and Methods: Between January 2002 and August 2012, orchiectomy specimens from 31 postpubertalpatients (aged12 or over) with cryptorchid testis were reviewed. The specimens were evaluated for ITGCN using immunohistochemical stains ofplacental-like alkaline phosphatase and Oct 3/4 with routine hematoxylin-eosin stain. Additionally, the degree of spermatogenesiswas assessed using the Johnsen score. Results: Mean age was 34 years (range, 17 to 74 years) at surgery. All patients were diagnosed as unilateral cryptorchidism. Onepatient (3.2%) of 20-year-old had ITGCN in surgical specimen with all positive markers. Histological assessment of spermatogenesisshowed that mean Johnsen score was 3.42 (range, 1 to 9). Majority of patients (27 of 31) presented impaired spermatogenesis withlow Johnsen score lesser than 5. Conclusions: Considering the risk of malignancy and low spermatogenesis, we should perform immunohistochemical stains anddiscuss preventative orchiectomy for the postpubertal cryptorchidism.

목차

등록된 정보가 없습니다.

참고문헌 (20)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0