지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 785 - 787 (3page)
이용수
초록· 키워드
오류제보하기
Heterophilic antibodies are human immunoglobulins directed against various animal antigens. They can produce false-positive results in the analysis of different tumor markers, including prostate-specific antigen. This interference can lead to misdiagnosis, unnecessary tests, and overtreatment in some cases. We present herein the case of a 52-year-old man with repeated spurious elevation of prostate-specific antigen, reaching levels of 108.7 ng/mL, that were suspected to be caused by heterophilic antibodies. The interference was solved by changing the analysis technique. Real values of prostate-specific antigen were less than 1 ng/mL.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Levinson SS / 2002 / Towards a better understanding of heterophile (and the like) antibody interference with modern immunoassays / Clin Chim Acta 325:1~15
Weber TH / 1990 / Endogenous interference in immunoassays in clinical chemistry: a review / Scand J Clin Lab Invest Suppl 201:77~82
Kricka LJ / 1990 / Interference by human anti-mouse antibody in two-site immunoassays / Clin Chem 36:892~894
Camacho T / 2002 / Falsely increased prostate-specific antigen concentration attributed to heterophilic antibodies / Ann Clin Biochem 39(Pt 2):160~161
Henry N / 2009 / Inappropriate treatment of prostate cancer caused by heterophilic antibody interference / Nat Clin Pract Urol 6:164~167
Weber TH / 1990 / Endogenous interference in immunoassays in clinical chemistry: a review / Scand J Clin Lab Invest Suppl 201:77~82
Kricka LJ / 1990 / Interference by human anti-mouse antibody in two-site immunoassays / Clin Chem 36:892~894
Camacho T / 2002 / Falsely increased prostate-specific antigen concentration attributed to heterophilic antibodies / Ann Clin Biochem 39(Pt 2):160~161
Henry N / 2009 / Inappropriate treatment of prostate cancer caused by heterophilic antibody interference / Nat Clin Pract Urol 6:164~167
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